Elemental composition of human milk from mothers of premature and full-term infants during the first 3 months of lactation
Elemental composition of human milk from mothers of premature and full-term infants during the first 3 months of lactation
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DOI：
10.1007/bf02784423
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发表时间：
1999-03-01
影响因子：
3.9
通讯作者：
Sutradhar, B
中科院分区：
文献类型：
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作者：
Friel, JK;Andrews, WL;Sutradhar, B
为了检验母乳中矿物质含量的纵向和妊娠效应，我们分析了居住在加拿大纽芬兰的早产儿(PRT，n=24，<；2000g出生体重，<；37wk)和足月儿(FT，n=19，>；2500g，39-41wk)哺乳母亲的母乳。每周采集一次样本，持续8wk，最后一次样本在3mo采集。采集在酸洗容器中的牛奶样品，用浓硝酸湿法灰化，用电感耦合等离子体质谱(EMS)测定钡、镉、钙、铯、钴、铜、铈、镧、镁、锰、钼、镍、铅、Rb、锡、锶和锌。使用标准的多元回归程序分析数据，并进行相关数据分析，以考虑到连续几周之间的关系。结果表明，PRT牛奶中的钙和铅含量较低。钙是唯一在营养上有意义的元素，不同组之间存在差异。PRT和FT牛奶中的钼随时间呈一定的下降趋势，说明牛奶中的钼含量是动态平衡调节的。然而，Ce、La、Ba和Sn没有表现出任何生物调节和潜在的人类需求的模式。
To examine longitudinal and gestational effects of mineral content in human milk, we analyzed human milk from lactating mothers of premature (PRT, n = 24, < 2000 g birth weight, < 37 wk gestation) and full-term (FT, n = 19, > 2500 g, 39-41 wk gestation), living in Newfoundland, Canada. Samples were collected once a week for 8 wk with one final sample collected at 3 mo. Milk samples collected in acid-washed containers were wet ashed with concentrated HNO3, and barium, cadmium, calcium, cesium, cobalt, copper, cerium, lanthanum, magnesium, manganese, molybdenum, nickel, lead, rubidium, tin, strontium, and zinc were measured using inductively coupled plasma-mass spectrometry. Data were analyzed using standard multiple-regression procedures with correlated data analyses to take account of the relationship between successive weeks. Results indicated lower Ca and Pb in PRT milk. Calcium was the only nutritionally significant element to differ between groups. Molybdenum in both PRT and FT milk showed a definite decrease with time, suggesting that the Mo content in milk is homeostatically regulated. However, Ce, La, Ba, and Sn did not display any pattern indicative of biological regulation and potential human requirement.