Eccentric endurance training in subjects with coronary artery disease: a novel exercise paradigm in cardiac rehabilitation?

Eccentric endurance training in subjects with coronary artery disease: a novel exercise paradigm in cardiac rehabilitation?
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冠状动脉疾病患者的离心耐力训练:心脏康复的新型运动范例?

DOI:
10.1007/s00421-003-1000-6
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发表时间:
2004
影响因子:
3
通讯作者:
H. Hoppeler
H. Hoppeler
中科院分区:
医学3区
文献类型:
--
作者:
R. Steiner;K. Meyer;K. Lippuner;J. Schmid;H. Saner;H. Hoppeler

文献摘要

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本研究评估了8周偏心耐力训练(EET)对患有冠状动脉疾病(CAD)的男性受试者(42-66岁)的影响。将EET与在相同代谢运动强度下进行的同心耐力训练(CET)进行比较,每周三次,每次半小时。CET (n=6)在传统的自行车劳力计上完成,EET (n=6)在定制的电机驱动的劳力计上完成。在训练计划的前5周,两组的代谢负荷逐渐增加到峰值摄氧量的60%。在这种代谢负荷下,CET的机械功率为97 (8)W [mean (SE)], EET的机械功率为338 (34)W。用双能x线吸收仪测定腿部肌肉质量,用等速测力仪测定股四头肌力量,用形态测定法测定股外侧肌的肌纤维组成。两组的腿部肌肉量都显著增加了约3%。仅在EET中,膝关节伸肌的强度参数得到改善。在60°s−1和120°s−1时,峰值等距扭矩和峰值同心扭矩分别达到+11(4.9)%、+15(3.2)%和+9(2.5)%的显著变化。仅在CET中,纤维尺寸显著增加了19%。综上所述,本研究表明EET在中年CAD患者中是可行的,并且通过增加肌肉力量比CET具有功能优势。两组的肌肉质量增加相似,而肌肉结构组成受到各自训练方案的不同影响。本研究的潜在局限性是谨慎选择条件反射方案和受试者数量有限。
This study evaluated the effects of 8 weeks of eccentric endurance training (EET) in male subjects (age range 42–66 years) with coronary artery disease (CAD). EET was compared to concentric endurance training (CET) carried out at the same metabolic exercise intensity, three times per week for half an hour. CET (n=6) was done on a conventional cycle ergometer and EET (n=6) on a custom-built motor-driven ergometer. During the first 5 weeks of the training program the metabolic load was progressively increased to 60% of peak oxygen uptake in both groups. At this metabolic load, mechanical work rate achieved was 97 (8) W [mean (SE)] for CET and 338 (34) W for EET, respectively. Leg muscle mass was determined by dual-energy X-ray absorptiometry, quadriceps strength with an isokinetic dynamometer and muscle fibre composition of the vastus lateralis muscle with morphometry. The leg muscle mass increased significantly in both groups by some 3%. Strength parameters of knee extensors improved in EET only. Significant changes of +11 (4.9)%, +15 (3.2)% and +9 (2.5)% were reached for peak isometric torque and peak concentric torques at 60° s−1 and 120° s−1, respectively. Fibre size increased significantly by 19% in CET only. In conclusion, the present investigation showed that EET is feasible in middle-aged CAD patients and has functional advantages over CET by increasing muscle strength. Muscle mass increased similarly in both groups whereas muscle structural composition was differently affected by the respective training protocols. Potential limitations of this study are the cautiously chosen conditioning protocol and the restricted number of subjects.