Pediatric solid tumors: evaluation by gallium-67 SPECT studies.
Pediatric solid tumors: evaluation by gallium-67 SPECT studies.
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儿童实体瘤：通过镓 67 SPECT 研究进行评估。
DOI：
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发表时间：
1990
影响因子：
9.3
通讯作者：
V. Nayanar
中科院分区：
文献类型：
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作者：
M. Rossleigh;I. Murray;D. Mackey;K. A. Bargwanna;V. Nayanar
对37例患有各种实体瘤的儿童进行了60次67 Ga单光子发射计算机断层扫描（SPECT）研究。这些研究与临床和放射学结果相关，并且在可能的情况下，与组织病理学确认相关。在所有研究中，SPECT比平面视图更好地定义和更好的病变部位解剖定位。SPECT在头部和颈部（平面16，SPECT 19）、胸部（平面39，SPECT 45）和腹部（平面22，SPECT 24）检测到更多病变。在化疗后扫描的20例患者中，SPECT在证明示踪剂在正常定位和形状的胸腺中的积聚表明胸腺再生而不是肿瘤复发引起的摄取方面是有用的。得出的结论是，67镓SPECT研究是非常有用的儿科人群，也许是因为他们的小尺寸，标准的平面视图的解释可能是困难的。
A retrospective review of 37 children with a variety of solid tumors who underwent 60 67Ga single-photon emission computed tomographic (SPECT) studies was performed. These studies were correlated with clinical and radiological findings and, where possible, histopathologic confirmation. In all studies, SPECT gave better definition and better anatomic localization of disease sites than obtained with planar views. SPECT detected more lesions in the head and neck (planar 16, SPECT 19), chest (planar 39, SPECT 45), and abdomen (planar 22, SPECT 24). In six of 20 patients scanned following chemotherapy, SPECT was useful in demonstrating that tracer accumulation in a normally located and shaped thymus indicated uptake resulting from thymic regeneration rather than tumor recurrence. It is concluded that 67Ga SPECT studies are very useful in the pediatric population, where perhaps because of their small size, interpretation of standard planar views may be difficult.