Evidence for the presence of rat alpha 1-acid glycoprotein in granuloma tissue: a fluorescence microscopy study.
Evidence for the presence of rat alpha 1-acid glycoprotein in granuloma tissue: a fluorescence microscopy study.
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肉芽肿组织中存在大鼠 α1-酸性糖蛋白的证据：荧光显微镜研究。
DOI：
10.1139/z80-209
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发表时间：
1980
影响因子：
1.4
通讯作者：
E. Huebner
中科院分区：
文献类型：
--
作者：
J. C. Jamieson;B. Turchen;E. Huebner
在大鼠身上产生松节油肉芽肿，用荧光标记抗体检测组织学和大鼠白蛋白和α1-酸性糖蛋白的存在。肉芽肿检查显示肉芽肿组织有结缔组织区；荧光抗α1-酸性糖蛋白染色较强，而荧光抗白蛋白染色较少。这些结果提示α1-酸性糖蛋白位于炎症部位，可能参与炎症过程的某些方面。
Turpentine granulomas were produced in rats and examined histologically and for the presence of rat albumin and α1-acid glycoprotein using fluorescent labelled antibody to these proteins. Examination of granulomas showed the presence of a connective tissue region of granuloma tissue; this region stained strongly with fluorescent anti-α1-acid glycoprotein whereas there was little staining with fluorescent antialbumin. These results suggest that α1-acid glycoprotein is located at the inflammatory site and may be involved in some aspect of the inflammatory process.