Consensus and Ancestral State HIV Vaccines

Consensus and Ancestral State HIV Vaccines
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共识和祖先状态艾滋病毒疫苗

DOI:
10.1126/science.299.5612.1515c
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发表时间:
2003
期刊:
影响因子:
56.9
通讯作者:
J. Mullins
J. Mullins
中科院分区:
综合性期刊1区
文献类型:
--
作者:
D. Nickle;M. Jensen;G. Gottlieb;D. Shriner;G. Learn;A. Rodrigo;J. Mullins

文献摘要

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B的评论。Gaschen等人(“Diversity considerations in HIV-1 vaccine selection,”28 June,p. [2354][1])描述了两种被考虑用于开发针对HIV的疫苗抗原的计算方法(共识和祖先状态)。这些方法试图最小化
The review by B. Gaschen et al . (”Diversity considerations in HIV-1 vaccine selection,” 28 June, p. [2354][1]) describes two computational methods (consensus and ancestral state) being considered for developing vaccine antigens against HIV. These methods attempt to minimize the amount of