Choroidal Melanoma Resection
Choroidal Melanoma Resection
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DOI：
10.4103/meajo.meajo_73_18
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发表时间：
2018-04-01
影响因子：
0.6
通讯作者：
Elhusseiny, Abdelrahman M.
中科院分区：
文献类型：
--
作者：
Hamza, Hany S.;Elhusseiny, Abdelrahman M.
葡萄膜黑色素瘤是最常见的眼内恶性肿瘤，脉络膜是最常见的网站。脉络膜黑色素瘤的治疗在过去几年中有了很大的发展。在过去，传统的治疗方法是摘除受影响的眼睛，关于摘除的效果，以促进或防止转移的辩论。然而，如今，有许多可用的治疗选择，包括斑块放射疗法、质子束放射疗法、氩激光光凝、经瞳孔温热疗法、使用伽玛刀的立体定向放射疗法、眼球摘除术和肿瘤的手术切除，无论是通过经巩膜途径“外切”还是不太常见的通过内部切除途径“内切除”。“每种技术的适应症和并发症进行了审查。虽然放射治疗是脉络膜黑色素瘤的主要治疗在大多数眼科肿瘤中心，它被用作辅助治疗与手术切除。内切除术前立体定向放射治疗以及外切除术和内切除术中手术床近距离放射治疗可以有效降低复发率。在这篇文章中，我们将集中讨论脉络膜黑色素瘤的手术切除，无论是内切除还是外切除。我们收集的数据发表在索引期刊和相关书籍。
Uveal melanoma is the most common intraocular malignant tumor, with the choroid being the most common site. Management of choroidal melanoma has evolved greatly over the past years. In the past, the conventional method of treatment was enucleation of the affected eye with a debate regarding the effect of enucleation to promote or prevent metastasis. However, nowadays, there are many therapeutic options available including plaque radiotherapy, proton beam radiotherapy, argon laser photocoagulation, transpupillary thermotherapy, stereotactic radiotherapy using gamma knife, enucleation, and surgical resection of the tumor whether through transscleral approach "Exoresection" or less commonly through internal resection approach "Endoresection." The indications and complications of each technique are reviewed. Although radiotherapy is the primary treatment of choroidal melanoma in most ocular oncology centers, it is used as an adjuvant therapy in combination with surgical resection. Preoperative stereotactic radiotherapy before endoresection and brachytherapy to the surgical bed in both exo and endoresection can effectively decrease the recurrence rate. In this article, we will focus on surgical resection of choroidal melanoma whether endoresection or exoresection. We collected data published in indexed journals and related books.