The carboxyl-terminal sequence of rat intestinal mucin RMuc3 contains a putative transmembrane region and two EGF-Like motifs

The carboxyl-terminal sequence of rat intestinal mucin RMuc3 contains a putative transmembrane region and two EGF-Like motifs
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DOI:
10.1016/s0005-2736(97)00063-1
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发表时间:
1997-05-22
影响因子:
3.4
通讯作者:
Forstner, JF
Forstner, JF
中科院分区:
生物学3区
文献类型:
--
作者:
Khatri, IA;Forstner, GG;Forstner, JF

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采用3' RACE技术构建了大鼠肠Muc 3蛋白C-末端379个氨基酸的核苷酸序列。与Muc 2和许多分泌性粘蛋白的C-末端不同,Muc 3含有两个EGF基序和一个假定的跨膜结构域。大鼠Muc 3的mRNA为7.5-8.0 kb。
A 3' RACE technique was used to establish the nucleotide sequence encoding the C-terminal 379 amino acids of rat intestinal Muc3. Unlike the C-terminus of Muc2 and many secretory mucins, Muc3 contains two EGF motifs and a putative transmembrane domain. The mRNA for rat Muc3 is 7.5-8.0 kb.