Minimizing the number of voltage sources and fluid reservoirs for electrokinetic valving in microfluidic devices
Minimizing the number of voltage sources and fluid reservoirs for electrokinetic valving in microfluidic devices
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DOI：
10.1021/ac990059s
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发表时间：
1999-08-01
影响因子：
7.4
通讯作者：
Ramsey, JM
中科院分区：
文献类型：
--
作者：
Jacobson, SC;Ermakov, SV;Ramsey, JM
一个微芯片门控阀的演示，使用一个单一的电压源和三个流体水库。射流阀是交叉的，并且通道的尺寸被设计为执行适当的分压，从而简化了电压控制硬件。单个电压源直接施加到样品储存器，并通过高压继电器施加到缓冲储存器，废液储存器接地。分配的样品体积由高压继电器断开的持续时间决定。体积重现性被证明是
A microchip gated valve is demonstrated that uses a single voltage source and three fluid reservoirs. The fluidic valve is a cross intersection, and the channels are dimensioned to perform the appropriate voltage division, simplifying the voltage control hardware. A single voltage source is applied directly to the sample reservoir and through a high-voltage relay to the buffer reservoir, and the waste reservoir is grounded. The volume of sample dispensed is determined by the duration that the high-voltage relay is open. Volumetric reproducibility is demonstrated to be