Microsclerodermins C-E, antifungal cyclic peptides from the lithistid marine sponges Theonella sp and Microscleroderma sp
Microsclerodermins C-E, antifungal cyclic peptides from the lithistid marine sponges Theonella sp and Microscleroderma sp
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DOI：
10.1016/s0040-4020(98)00054-4
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发表时间：
1998-03-26
期刊：
影响因子：
2.1
通讯作者：
Faulkner, DJ
中科院分区：
文献类型：
--
作者：
Schmidt, EW;Faulkner, DJ
从菲律宾米沙鄢群岛的两种石海绵中分离到三个新的环肽，即microsclerodermins C-E（3-5）。海绵Theonella sp.含有肽3和4，而Microscleroderma sp.含有肽4和5。它们的结构，其中具有三个前所未有的氨基酸，使用光谱方法和化学降解进行了阐明。(C)1998爱思唯尔科技有限公司。保留所有权利。
Three new cyclic peptides, microsclerodermins C-E (3-5), were isolated from two species of lithistid sponges from the Visayan Islands, Philippines. The sponge Theonella sp. contained peptides 3 and 4, while Microscleroderma sp. contained peptides 4 and 5. Their structures, which feature three unprecedented amino acids, were elucidated using spectroscopic methods and chemical degradation. (C) 1998 Elsevier Science Ltd. All rights reserved.