Effectiveness of an intervention campaign on influenza vaccination of professionals in nursing homes: A cluster-randomized controlled trial
Effectiveness of an intervention campaign on influenza vaccination of professionals in nursing homes: A cluster-randomized controlled trial
复制标题
DOI：
10.1016/j.vaccine.2019.01.066
复制
发表时间：
2019-02-28
期刊：
影响因子：
5.5
通讯作者：
Thibon, Pascal
中科院分区：
文献类型：
--
作者：
Borgey, France;Henry, Liliane;Thibon, Pascal
背景：季节性流感对个人和集体都有重大影响，尤其是在养老院的老年人中。要预防流感病毒感染，为居民和专业人士注射疫苗是一项重要措施。然而，虽然居民的疫苗接种率普遍较高（>85%），但专业人员的接种率通常约为20%。为了评估干预活动对专业人员流感疫苗接种率提高的有效性，提出了一项区域干预研究，在2014-15赛季的养老院。方法：随机对照试验（养老院代表一个集群）。在干预组，向工作人员提供了流感疫苗接种运动，以多模式方法结合不同的教具。在对照组中，没有提出任何干预措施。主要终点是工作人员的流感疫苗接种率。在研究之前和之后，专业人员被要求完成关于他们对流感疫苗接种的看法的简短问卷。多层次分析进行了比较两组之间的疫苗接种率和他们的演变之前/之后的冬季period.Results：共32个养老院被随机化，6个被排除。干预组和对照组的初始疫苗接种率分别为27.6%和24.2%（p = 0.16）。研究结束后，这两个比率分别上升到33.7%和22.9%，干预组与对照组的相对差异为+22.1%和-5.4%，p = 0.0025。结论：尽管专业人员不愿意接种疫苗，但以务实的方式参与宣传活动提高了流感疫苗接种率。在对工具进行修订以提高其易用性和侧重于专业人员直接受益的教学信息之后，将向该区域所有养老院提供这一方法。(C)2019爱思唯尔有限公司版权所有。
Background: Seasonal influenza has a major individual and collective impact, especially among the elderly living in nursing homes. To prevent infection by influenza viruses, vaccination of residents and professionals is an essential measure. However, while the vaccination rates of residents are generally high (>85%), rates among professionals are generally approximately 20%. To evaluate the effectiveness of an intervention campaign on the improvement of the influenza vaccination rate of professionals, a regional intervention study was proposed for nursing homes during the 2014-15 season.Methods: Cluster-randomized controlled trial (with a nursing home representing a cluster). In the intervention group, a campaign on influenza vaccination was offered to staff, combining different teaching aids in a multimodal approach. In the control group, no intervention was proposed. The primary endpoint was the rate of influenza vaccination among staff. Before and after the study, professionals were asked to complete short questionnaires on their perceptions of influenza vaccination. A multilevel analysis was carried out to compare the vaccination rates between the 2 groups and their evolution before/after the winter period.Results: A total of 32 nursing homes were randomized, and 6 were excluded. Initial vaccination rates were 27.6% in the intervention group and 24.2% in the control group (p = 0.16). After the study, these rates increased to 33.7% and 22.9%, respectively, which was a relative difference of +22.1% in the intervention group compared to -5.4% in the control group, p = 0.0025.Conclusions: Despite professionals' reluctance to be vaccinate, participation in a promotional campaign with a pragmatic approach has increased the rate of influenza vaccination. The approach will be offered to all nursing homes in the region after revision of the tools to enhance their ease of use and pedagogical messages focused on the direct benefits to professionals. (C) 2019 Elsevier Ltd. All rights reserved.