A serpentine laminating micromixer combining splitting/recombination and advection
A serpentine laminating micromixer combining splitting/recombination and advection
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DOI：
10.1039/b418314b
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发表时间：
2005-01-01
期刊：
影响因子：
6.1
通讯作者：
Ahn, CH
中科院分区：
文献类型：
--
作者：
Kim, DS;Lee, SH;Ahn, CH
混合增强引起了微混合器设计者的高度关注，因为微通道内的流动通常具有低雷诺数（Re）的特征，这使得混合很难完成。本文设计、模拟、制作了一种新型高效集成微混合器——蛇形复合微混合器，并对其进行了全面表征。在SLM中，通过结合两种一般的混沌混合机制：分裂/重组和混沌平流，可以实现高水平的高效混合。分裂和复合（换句话说，层压）机制是通过在两层中连续排列“F”形混合单元获得的。平流是由微通道的整体三维蛇形路径引起的。采用SU-8光刻、电镀镍、注塑、热粘合等工艺实现了SLM。通过数值和实验对SLM的混合性能进行了充分的表征。数值混合模拟结果表明，平流有利于实现理想的流体垂直分层。基于酚酞混合色强平均变化的混合实验表明，SLM具有较高的混合性能。数值和实验结果证实，SLM在很大的Re范围内成功地实现了高效混合。由于本研究中提出的高效微混合器的简单和可批量生产的几何形状，SLM可以很容易地应用于集成微流体系统，如微总量分析系统或芯片实验室系统。
Mixing enhancement has drawn great attention from designers of micromixers, since the flow in a microchannel is usually characterized by a low Reynolds number ( Re) which makes the mixing quite a difficult task to accomplish. In this paper, a novel integrated efficient micromixer named serpentine laminating micromixer (SLM) has been designed, simulated, fabricated and fully characterized. In the SLM, a high level of efficient mixing can be achieved by combining two general chaotic mixing mechanisms: splitting/recombination and chaotic advection. The splitting and recombination ( in other terms, lamination) mechanism is obtained by the successive arrangement of "F''-shape mixing units in two layers. The advection is induced by the overall three-dimensional serpentine path of the microchannel. The SLM was realized by SU-8 photolithography, nickel electroplating, injection molding and thermal bonding. Mixing performance of the SLM was fully characterized numerically and experimentally. The numerical mixing simulations show that the advection acts favorably to realize the ideal vertical lamination of fluid flow. The mixing experiments based on an average mixing color intensity change of phenolphthalein show a high level of mixing performance was obtained with the SLM. Numerical and experimental results confirm that efficient mixing is successfully achieved from the SLM over the wide range of Re. Due to the simple and mass producible geometry of the efficient micromixer, SLM proposed in this study, the SLM can be easily applied to integrated microfluidic systems, such as micro-total-analysis-systems or lab-on-a-chip systems.