A mild and efficient protocol for the conversion of carboxylic acids to olefins by a catalytic decarbonylative elimination reaction
A mild and efficient protocol for the conversion of carboxylic acids to olefins by a catalytic decarbonylative elimination reaction
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DOI：
10.1039/b316613a
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发表时间：
2004-03-21
影响因子：
4.9
通讯作者：
Rodríguez, N
中科院分区：
文献类型：
--
作者：
Goossen, LJ;Rodríguez, N
公开了一种在前所未有的温和条件下将脂肪族羧酸转化为烯烃的新方法，其中所述羧酸与偏戊酸酐原位转化为混合酸酐，所述混合酸酐区域选择性地添加到PdCl2-DPE-PHOS催化剂中。在仅110℃的温度下，发生平稳的脱碳和β-氢化物消除，相应的烯烃以及CO、CO2和新戊酸被释放出来。
A new method for the conversion of aliphatic carboxylic acids to olefins under unprecedented mild conditions is disclosed, wherein the carboxylic acids are converted in situ with pivalic anhydride to the mixed anhydrides, which regioselectively add to a PdCl2-DPE-Phos catalyst. At a temperature of only 110 degreesC, smooth decarbonylation and beta-hydride elimination occur, and the corresponding olefins along with CO, CO2 and pivalic acid are liberated.