Normalizing fractional moving blood volume estimates with power Doppler US: Defining a stable intravascular point with the cumulative power distribution function
Normalizing fractional moving blood volume estimates with power Doppler US: Defining a stable intravascular point with the cumulative power distribution function
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DOI：
10.1148/radiology.205.3.9393532
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发表时间：
1997-12-01
期刊：
影响因子：
19.7
通讯作者：
Adler, RS
中科院分区：
文献类型：
--
作者：
Rubin, JM;Bude, RO;Adler, RS
目的：为了将能量多普勒超声(US)信号归一化到100%血液中的期望信号，在计算运动血容量分数时，材料和方法：为了用一致的后向散射系数来定位来自流动血液的信号，作者估计了累积多普勒功率分布函数的膝部。他们使用现在管状的体模来测试这个膝盖的使用，以定位一个径向位置，该位置将落入高剪应力和最小的绳索形成区域。他们还研究了当模拟不同的身体习惯时，该方法对志愿者右肾皮质部分运动血容量估计的归一化程度，并在一组6名健康志愿者中估计变异性。结果：超过5个流速和过不饱和到严重过饱和的接收器增益，计算的Now-Tube面积是标准的平均89%+/-7(+/-标准差)。在人体中，该技术在8分贝接收增益变化范围内归一化了分数运动血流量估计值；6名志愿者的分数运动血流量估计值的平均+/-标准差为37.6%+/-3.6。结论：采用基于累积多普勒功率分布函数的归一化方案，能量多普勒超声对血管密度的估计是可行的。
PURPOSE: To normalize the power Doppler ultrasound (US) signal to the expected signal from 100% blood in the calculation of a fractional moving blood volume estimate.MATERIALS AND METHODS: To locate the signal from flowing blood with a consistent backscatter coefficient, the authors estimated the knee of the cumulative Doppler power distribution function. They used a now-tube phantom to test the use of this knee to locate a radial position that would fall into a region of high sheer stress and minimal rouleaux formation. They also studied how well the method normalized fractional moving blood volume estimates of the right renal cortex in a volunteer when simulating different body habitus and in a group of six healthy volunteers to estimate variability.RESULTS: Over five flow velocities and over undersaturated to severely oversaturated receiver gains, the calculated now-tube area was a mean 89% +/- 7 (+/- standard deviation) of a standard. In humans, the technique normalized the fractional moving blood volume estimates over an 8-dB receiver gain variation; the mean +/- standard deviation of fractional moving blood volume estimates for the six volunteers was 37.6% +/- 3.6.CONCLUSION: Vascularity estimates with power Doppler US are feasible with a normalization scheme based on the cumulative Doppler power distribution function.