Outcome of universal newborn eye screening with wide-field digital retinal image acquisition system: a pilot study
Outcome of universal newborn eye screening with wide-field digital retinal image acquisition system: a pilot study
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DOI：
10.1038/eye.2017.129
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发表时间：
2018-01-01
期刊：
影响因子：
3.9
通讯作者：
Jalali, S.
中科院分区：
文献类型：
--
作者：
Goyal, P.;Padhi, T. R.;Jalali, S.
目的评估结果的普遍新生儿眼筛查与宽视野数字视网膜成像（WFDRI）system.Methods在这项试点研究中，我们检查了1152显然健康的新生儿在产科和妇科病房在印度东部的一家民用医院超过1.5年。检查包括由经过培训的验光师进行的外眼检查、红色反射测试和WFDRI（RetCam II，Clarity medical system，普莱森顿，CA，USA）眼底成像。记录了所发现的病症、净货币收益和节省的熟练人力。结果172例（14.93%）新生儿出现各种眼部异常。视网膜出血153例（占异常的88.9%），双侧118例（77.12%），中心凹出血4例。其他异常包括玻璃体出血（n = 1）、先天性青光眼（n = 2）、葡萄膜缺损（n = 2）、类似早产儿视网膜病变的视网膜病变（n = 2）和囊状中心凹（n = 3）。所有患眼的视网膜病变均自行消退。一名患有先天性青光眼的婴儿接受了手术，另一名接受了药物治疗。的好处包括节省熟练的人力资源，净货币收益419.5万印度卢比（62,612美元）和熟练的人力资源节省319.4 h。结论普遍新生儿眼部筛查使用WFDRI检测病理，需要立即护理或定期随访，节省熟练的人力资源与净货币收益。但与红色反射测试相比，在检测治疗预防眼部病变方面的益处是微不足道的。
Purpose To evaluate the outcome of universal newborn eye screening with widefield digital retinal imaging (WFDRI) system.Methods In this pilot study, we examined 1152 apparently healthy newborn infants in the obstetrics and gynecology ward of a civil hospital in Eastern India over 1.5 years. The examination included external eye examination, red reflex test and fundus imaging by WFDRI (RetCam II, Clarity medical system, Pleasanton, CA, USA) by a trained optometrist. The pathologies detected, net monetary gain and skilled manpower saved were documented. The results were compared with three similar studies thus far published in the literature.Results Ocular abnormality of any kind was seen in 172 (14.93%) babies. Retinal hemorrhage in 153 babies (88.9% of all abnormal findings) was the most common abnormality; it was bilateral in 118 (77.12%) babies and 4 babies had foveal hemorrhage. Other abnormalities included vitreous hemorrhage (n = 1), congenital glaucoma (n = 2), uveal coloboma (n = 2), retinopathy mimicking retinopathy of prematurity (n = 2), and cystic fovea (n = 3). The retinal hemorrhages resolved spontaneously in all eyes. One baby with congenital glaucoma received surgery and the other was treated medically. The benefits included savings in skilled manpower, a net monetary gain of INR 4.195 million (US$ 62,612) and skilled manpower saving by 319.4 h.Conclusions The universal neonatal eye screening using WFDRI detected pathologies that needed immediate care or regular follow up; saved skilled manpower with a net monetary gain. But compared to a red reflex test the benefits were marginal in terms of detecting treatment warranting ocular pathologies.