Current research in child and adolescent bipolar disorder.
Current research in child and adolescent bipolar disorder.
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当前儿童和青少年双相情感障碍的研究。
DOI：
10.31887/dcns.2008.10.2/cademeter
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发表时间：
2008
影响因子：
8.3
通讯作者：
Findling RL
中科院分区：
文献类型：
--
作者：
Demeter CA;Townsend LD;Wilson M;Findling RL
尽管与过去相比，最近有更多的研究考虑了患有双相情感障碍的儿童，但围绕诊断的有效性仍然存在许多争议。此外，问题仍然是儿童时期的双相情感障碍的表现是否持续与成人的疾病表现。为了提高目前对儿童双相情感障碍的认识，研究人员已经开始对表现出双相情感障碍症状的青少年以及双相情感障碍父母的后代进行现象学、纵向、治疗和神经影像学研究。尽管不同的研究小组对儿童双相情感障碍的定义不同，但一致认为儿童双相情感障碍是一种严重且有害的疾病。在青少年表现出儿童双相情感障碍的亚综合征症状期间进行早期干预，似乎可以避免疾病向更恶性表现的发展。本文将回顾目前已知的和仍有待学习的关于儿童和青少年双相情感障碍的临床突出主题。
Although recently more research has considered children with bipolar disorder than in the past, much controversy still surrounds the validity of the diagnosis. Furthermore, questions remain as to whether or not childhood expressions of bipolarity are continuous with adult manifestations of the illness. In order to advance current knowledge of bipolar disorders in children, researchers have begun to conduct phenomenological, longitudinal, treatment, and neuroimaging studies in youths who exhibit symptoms of bipolar illness, as well as offspring of parents with bipolar disorders. Regardless of the differences between research groups regarding how bipolar disorder in children is defined, it is agreed that pediatric bipolarity is a serious and pernicious illness. With early intervention during the period of time in which youths are exhibiting subsyndromal symptoms of pediatric bipolarity, it appears that the progression of the illness to the more malignant manifestation of the disorder may be avoided. This paper will review what is currently known and what still is left to learn about clinically salient topics that pertain to bipolar disorder in children and adolescents.