Detecting phase singularities and rotor center trajectories based on the Hilbert transform of intraatrial electrograms in an atrial voxel model
Detecting phase singularities and rotor center trajectories based on the Hilbert transform of intraatrial electrograms in an atrial voxel model
复制标题
基于心房体素模型中心房内电图的希尔伯特变换检测相位奇点和转子中心轨迹
DOI：
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发表时间：
2015
期刊：
影响因子：
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通讯作者：
O. Dössel
中科院分区：
文献类型：
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作者：
L. Unger;Markus Rottmann;G. Seemann;O. Dössel
摘要本工作旨在基于相位奇异性检测心房颤动时心房腔内的转子中心。建立了一种基于体素的方法，该方法采用希尔伯特变换和单极电图的相位。该方法提供了在内皮表面和血液体积内的相位奇点的3D概览。从心房内部在内径处映射这些相位奇点产生转子中心轨迹。我们讨论了不稳定和更稳定的转子的结果。轨迹所覆盖区域的边长从1.5 mm到10 mm不等。这些结果对于心脏病专家来说非常重要，他们用射频消融术靶向转子以治疗房颤。
Abstract This work aimed at the detection of rotor centers within the atrial cavity during atrial fibrillation on the basis of phase singularities. A voxel based method was established which employs the Hilbert transform and the phase of unipolar electrograms. The method provides a 3D overview of phase singularities at the endocardial surface and within the blood volume. Mapping those phase singularities from the inside of the atria at the endocardium yielded rotor center trajectories. We discuss the results for an unstable and a more stable rotor. The side length of the areas covered by the trajectories varied from 1.5 mm to 10 mm. These results are important for cardiologists who target rotors with RF ablation in order to cure atrial fibrillation.