Rapid response to cognitive behavior therapy predicts treatment outcome in patients with irritable bowel syndrome.
Rapid response to cognitive behavior therapy predicts treatment outcome in patients with irritable bowel syndrome.
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DOI：
10.1016/j.cgh.2010.02.007
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发表时间：
2010-05
影响因子：
12.6
通讯作者：
Katz, Leonard A.
中科院分区：
文献类型：
--
作者：
Lackner, Jeffrey M.;Gudleski, Gregory D.;Keefer, Laurie;Krasner, Susan S.;Powell, Cathrine;Katz, Leonard A.
We sought to determine whether the therapeutic phenomenon of rapid response characterizes patients undergoing CBT for irritable bowel syndrome (IBS). If RR is operating in IBS treatment, a significant proportion of CBT treated patients should achieve a positive response early in treatment (by week 4). We also hypothesized that rapid responders (RR) would be more likely to maintain treatment gains than non rapid responders (NRR). Our secondary goal was to characterize the psychosocial profile of RRs on clinically relevant demographic and clinical variables (e.g., health status, baseline level of IBS symptom severity, distress). 71 individuals ages 18–70 years with a Rome II IBS diagnosis and symptoms of at least moderate severity were randomized to one of 2 CBT treatments: either 10 weekly, one hour sessions (Standard-CBT) or four, one hour sessions over 10 weeks (Minimal Contact-CBT). RRs were classified as patients who 1) reported adequate relief of pain; 2), adequate relief of GI symptoms and 3) a decrease in total IBSSS scores of ≥50 by week 4. 30% of CBT treated patients achieved RR by week 4 of treatment. 90–95% of RRs maintained gains at immediate and 3 month follow-up. While RR reported more severe IBS symptoms at baseline, they achieved more substantial and sustained gains (e.g. IBS symptom reduction) than NRRs. Standard- and MC CBT yielded comparable RR rates even though MC CBT patients received 50% less clinic treatment by week 4. Rapid response is a potentially important prognostic outcome indicator that has important implications for developing step care approaches for IBS treatment.
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影响因子：
29.4
作者：
Drossman, DA;Toner, BB;Bangdiwala, SI
通讯作者：
Bangdiwala, SI
DOI：
10.1111/j.1468-2850.1994.tb00016.x
发表时间：
1994-12-01
影响因子：
5.8
作者：
ILARDI, SS;CRAIGHEAD, WE
通讯作者：
CRAIGHEAD, WE
影响因子：
9.8
作者：
Boyce, PM;Talley, NJ;Truman, G
通讯作者：
Truman, G
影响因子：
16.4
作者：
HOWARD, KI;KOPTA, SM;ORLINSKY, DE
通讯作者：
ORLINSKY, DE
影响因子：
5.9
作者：
Krupnick, JL;Sotsky, SM;Pilkonis, PA
通讯作者：
Pilkonis, PA