Lithium and Pregnancy—I, Report from the Register of Lithium Babies
Lithium and Pregnancy—I, Report from the Register of Lithium Babies
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DOI：
10.1136/bmj.2.5859.135
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发表时间：
1973-04
影响因子：
--
通讯作者：
M. Schou;M. Goldfield;M. Weinstein;A. Villeneuve
中科院分区：
文献类型：
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作者：
M. Schou;M. Goldfield;M. Weinstein;A. Villeneuve
我们收集了118名在怀孕前三个月接受锂治疗的母亲所生的孩子的信息。数据显示，致畸作用的风险低于对大鼠和小鼠进行的一些研究的预期;它们没有回答锂是否对人类具有致畸性的问题。数据是回顾性收集的，因此高估而不是低估了致畸性的风险。
We have collected information about 118 children born to mothers who were given lithium treatment during the first trimester of pregnancy. The data show that the risk of teratogenic effects is lower than one might have expected from some of the studies carried out on rats and mice; they do not answer the question of whether or not lithium is teratogenic in man. The data were collected retrospectively and therefore overestimate rather than underestimate the risk of teratogenicity.