No clinical relevance of the height of fundal indentation in subseptate or arcuate uterus: a prospective study
No clinical relevance of the height of fundal indentation in subseptate or arcuate uterus: a prospective study
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DOI：
10.1016/j.rbmo.2012.01.025
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发表时间：
2012-05-01
影响因子：
4
通讯作者：
Gianaroli, Luca
中科院分区：
文献类型：
--
作者：
Gergolet, Marco;Campo, Rudi;Gianaroli, Luca
美国生育协会将弓形子宫归类为临床行为良性的轻微畸形。这项前瞻性研究的目的是验证这种差异是否有任何科学基础。至少有一次早期流产且子宫半间隔或弓形的患者入院接受宫腔成形术。患者被分成凹陷大于或等于1.5 cm的亚中隔子宫组，或凹陷较小的弓形子宫组。两组子宫成形术后流产率相似(隔下子宫组14.0%，弓形子宫组11.1%)。宫腔成形术前，中隔子宫组和弓形子宫组的流产率明显高于中隔子宫组(均P<；0.001)。根据这些结果，无论是在手术矫正畸形之前还是之后，都没有证据支持弓形子宫与下纵隔子宫对生殖结局的不同影响。由于没有对弓形子宫进行单独分类的科学依据，因此有必要对子宫先天性异常的分类进行审查。(C)2012，爱思唯尔有限公司出版，生殖保健有限公司。保留所有权利。
The American Fertility Society has classified the arcuate uterus as a minor malformation with a benign clinical behaviour. The aim of this prospective study was to verify whether there is any scientific basis for this differentiation. Patients with at least one early miscarriage and a subseptate or arcuate uterus were admitted for hysteroscopic metroplasty. Patients were allocated to a subseptate uterus group, with an indentation of 1.5 cm or more, or an arcuate uterus group, with a smaller indentation. The miscarriage rates after metroplasty were similar between the two groups (14.0% in the subseptate uterus group versus 11.1% in the arcuate uterus group). Before metroplasty, the miscarriage rates were significantly higher in subseptate uterus group, as well as in the arcuate uterus group (both P < 0.001). According to these results, there is no evidence to support that the arcuate uterus has a different effect on the reproductive outcome in comparison to the subseptate uterus, neither before nor after surgical correction of the anomaly. Since there is no scientific basis for a separate classification of the arcuate uterus, a review of the classifications of uterine congenital anomalies should be considered as necessary. (C) 2012, Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.