Mycotic Abdominal Aortic Aneurysm after Adjuvant Therapy with Bacillus Calmette-Guerin in Patients with Urothelial Bladder Cancer: A Rare but Misinterpreted Complication
Mycotic Abdominal Aortic Aneurysm after Adjuvant Therapy with Bacillus Calmette-Guerin in Patients with Urothelial Bladder Cancer: A Rare but Misinterpreted Complication
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DOI：
10.1016/j.avsg.2015.01.036
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发表时间：
2015-08-01
影响因子：
1.5
通讯作者：
Lorenzi, Giovanni
中科院分区：
文献类型：
--
作者：
Leo, Enrico;Molinari, Alessandro L. C.;Lorenzi, Giovanni
卡介苗治疗通常伴有副作用。最可怕的是弥散性败血症，这种情况很少发生在霉菌性主动脉瘤的发展中。文献报道膀胱内卡介苗合并真菌性腹主动脉瘤患者20例，其中本研究2例。延迟血管检查是一个关键方面。霉菌性动脉瘤进展迅速。初级保健医生和泌尿科医生应敏感地识别未明确的症状，如真菌性腹主动脉瘤的潜在临床表现，甚至在卡介苗治疗后数月或数年。
Bacillus Calmette-Guerin (BCG) therapy is often associated with side effects. The most feared is disseminated sepsis that may occur rarely with the development of mycotic aortic aneurysms. Twenty cases of patients treated with intravesical BCG complicated by mycotic abdominal aortic aneurysm have been reported in the literature, including 2 cases of the present study. Delayed vascular work-up represents a critical aspect. Mycotic aneurysms evidence a rapid progression. Primary care physicians and urologists should be sensitized to recognize unspecified symptoms such as potential clinical manifestations of a mycotic abdominal aortic aneurysm, even several months or years after BCG therapy.