Necrotizing enterocolitis: controversies and challenges.

Necrotizing enterocolitis: controversies and challenges.
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DOI:
10.12688/f1000research.6888.1
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发表时间:
2015-01-01
期刊:
影响因子:
--
通讯作者:
Pierro, Agostino
Pierro, Agostino
中科院分区:
其他
文献类型:
--
作者:
Zani, Augusto;Pierro, Agostino

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坏死性小肠结肠炎是一种严重的肠道疾病,约有5%的早产儿患病。尽管新生儿护理取得了进步,但死亡率仍然很高(30-50%),关于新生儿坏死性小肠结肠炎的最适当管理仍然存在争议。在此,我们回顾了一些有争议的方面的流行病学,影像学,内科和外科治疗坏死性小肠结肠炎,我们描述了新出现的预防和治疗策略。
Necrotizing enterocolitis is a devastating intestinal disease that affects ~5% of preterm neonates. Despite advancements in neonatal care, mortality remains high (30-50%) and controversy still persists with regards to the most appropriate management of neonates with necrotizing enterocolitis. Herein, we review some controversial aspects regarding the epidemiology, imaging, medical and surgical management of necrotizing enterocolitis and we describe new emerging strategies for prevention and treatment.