Procalcitonin Levels in Acute Respiratory Infection.
Procalcitonin Levels in Acute Respiratory Infection.
复制标题
急性呼吸道感染中的降钙素原水平。
DOI：
10.1089/vim.2015.0106
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发表时间：
2016
期刊：
影响因子：
2.2
通讯作者：
Barrett,Bruce
中科院分区：
文献类型：
--
作者：
Henriquez,KelseyM;Hayney,MaryS;Rakel,DavidP;Barrett,Bruce
降钙素原（PCT）是炎症的一种生物标志物，用于帮助做出临床决策，比如开始使用抗生素或让病人住院。虽然PCT在肺炎中的水平已被广泛研究，但在不太严重的急性呼吸道感染（ARI）中的水平尚未得到很好的研究。为了测量急性呼吸道感染期间健康成人的PCT水平，我们在感冒和流感季节对99名健康成人进行了随访，在基线和参与者出现急性呼吸道感染时收集血液标本进行PCT检测。96%的ARI样本的PCT水平<0.05 ng/mL。其余4% <0.25 ng/mL。这些数据表明PCT在轻度至中度严重程度的ARI中不是一个有用的测试。
Procalcitonin (PCT) is a biomarker of inflammation that is used to help make clinical decisions, like starting antibiotics or admitting a patient to the hospital. While PCT levels have been widely studied in pneumonia, levels in less severe acute respiratory infections (ARI) have not been well studied. To measure PCT levels in otherwise healthy adults during ARI, we followed 99 healthy adults during the cold and flu season, collecting blood specimens for PCT testing at baseline, and when participants presented with ARI. Ninety-six percent of the ARI samples had PCT levels <0.05 ng/mL. The remaining 4% were <0.25 ng/mL. These data suggest that PCT is not a useful test in ARI of mild-to-moderate severity.