Medical Burden of Disease Among Individuals in Recovery From Alcohol and Other Drug Problems in the United States: Findings From the National Recovery Survey
Medical Burden of Disease Among Individuals in Recovery From Alcohol and Other Drug Problems in the United States: Findings From the National Recovery Survey
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DOI：
10.1097/adm.0000000000000512
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发表时间：
2019-09-01
影响因子：
5.5
通讯作者：
Kelly, John F.
中科院分区：
文献类型：
--
作者：
Eddie, David;Greene, M. Claire;Kelly, John F.
目的：酒精和其他药物（AOD）问题的医疗后遗症确切的个人和社会成本巨大，但鲜为人知的是，这种医疗问题的具体患病率，以及它们与生活质量和幸福指数之间的关系，从有问题的AOD使用中恢复。为了更好地描述终身身体疾病负担，本研究调查了美国成年人在AOD问题恢复中的全国代表性样本中过度和慢性AOD暴露通常引起或加重的医疗状况的患病率。与美国普通人群进行了比较。还调查了疾病患病率的人口统计学和临床相关性沿着不同医疗状况与生活质量/福祉指数之间的关系。方法：横断面全国代表性调查的美国成年人口谁报告解决一个AOD问题（n = 2002）。估计常见疾病的加权终生患病率，并与美国人口进行比较。人口统计学和临床相关的医疗条件，以及整体疾病负担，估计使用逻辑回归。结果如下：相对于普通人群，丙型肝炎、慢性阻塞性肺病、心脏病和糖尿病的患病率升高。终生诊断特定疾病的可能性与使用的主要药物和性别有关。有身体疾病史者的生活质量较无身体疾病史者低。结论：研究结果强调了与AOD问题相关的医疗负担增加，并谈到需要更早和更持续的干预AOD问题，更大程度地整合成瘾治疗和初级卫生保健，以及纵向研究，以探索AOD使用和身体疾病之间的复杂，动态的关系。
Objectives: The medical sequalae of alcohol and other drug (AOD) problems exact a prodigious personal and societal cost, but little is known about the specific prevalence of such medical problems, and their relationship to quality of life and indices of well-being among those recovering from problematic AOD use. To better characterize the lifetime physical disease burden, this study investigated the prevalence of medical conditions commonly caused or exacerbated by excessive and chronic AOD exposure in a nationally representative sample of US adults in AOD problem recovery. Comparisons were made to the general US population. Demographic and clinical correlates of disease prevalence were also investigated along with the relationship between distinct medical conditions and indices of quality of life/well-being. Methods: Cross-sectional nationally representative survey of the US adult population who report resolving an AOD problem (n = 2002). Weighted lifetime prevalence of common medical conditions were estimated and compared to the US population. Demographic and clinical correlates of medical conditions, and also overall disease burden, were estimated using logistic regression. Results: Relative to the general population, prevalence of hepatitis C, chronic obstructive pulmonary disease, heart disease, and diabetes were elevated. Likelihood of having a lifetime diagnosis of a specific disease was related to primary substance used and sex. Quality of life was lower among those with physical disease histories relative to those without. Conclusions: Findings highlight the increased medical burden associated with AOD problems, and speak to the need for earlier and more sustained intervention for AOD problems, greater integration of addiction treatment and primary health care, and longitudinal research to explore the complex, dynamic relationships between AOD use and physical disease.