Noninvasive Diagnosis of Infection Using Plasma Next-Generation Sequencing: A Single-Center Experience
Noninvasive Diagnosis of Infection Using Plasma Next-Generation Sequencing: A Single-Center Experience
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DOI：
10.1093/ofid/ofz327
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发表时间：
2019-08-01
影响因子：
4.2
通讯作者：
Muller, William J.
中科院分区：
文献类型：
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作者：
Rossoff, Jenna;Chaudhury, Sonali;Muller, William J.
儿科患者经常出现强烈提示感染的疾病，但没有明确的病因。我们的中心最近在其现有的诊断测试中增加了一种市售的血浆宏基因组测序测定。我们前100次测试的经验表明，该技术具有良好的临床性能，灵敏度>90%。
Pediatric patients frequently present with illnesses strongly suggesting infection, but without a clearly identified etiology. Our center has recently added a commercially available plasma metagenomic sequencing assay to its available diagnostic testing. Our experience with the first 100 tests suggests that this technology has good clinical performance with >90% sensitivity.