Electrospinning of poly(ethylene-co-vinyl alcohol) fibers
Electrospinning of poly(ethylene-co-vinyl alcohol) fibers
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DOI：
10.1016/s0142-9612(02)00422-2
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发表时间：
2003-03-01
期刊：
影响因子：
14
通讯作者：
Wnek, GE
中科院分区：
文献类型：
--
作者：
Kenawy, ER;Layman, JM;Wnek, GE
乙烯-乙烯醇共聚物或 EVOH 溶液的组成为 56 至 71 wt% 乙烯醇，可在室温下从 70% 2-丙醇/水（外用酒精）溶液中轻松进行静电纺丝。溶液在 80°C 下制备并冷却至室温。有趣的是，溶液在室温下不稳定，最终聚合物在几个小时后沉淀。然而，在沉淀之前，静电纺丝是广泛且快速的，允许纤维覆盖各种基材上，包括接地的金属板、插入带电射流和金属接地之间的电介质以及人体上。纤维直径约。根据溶液浓度获得 0.2-8.0 μm，这对于组织工程、伤口愈合和相关应用来说是一个有吸引力的范围。静电纺丝 EVOH 垫已被证明可以支持平滑肌细胞和成纤维细胞的培养。 (C) 2002 Elsevier Science Ltd. 保留所有权利。
Solutions of poly(ethylene-co-vinyl alcohol) or EVOH, ranging in composition from 56 to 71 wt% vinyl alcohol, can be readily electrospun at room temperature from solutions in 70% 2-propanol/water (rubbing alcohol). The solutions are prepared at 80degreesC and allowed to cool to room temperature. Interestingly, the solutions are not stable at room temperature and eventually the polymer precipitates after several hours. However, prior to precipitation, electrospinning is extensive and rapid, allowing coverage of fibers on various substrates, including a grounded metal plate, dielectrics interposed between the charged jet and the metal ground, and on the human body. Fiber diameters of ca. 0.2-8.0 mum were obtained depending upon the solution concentration, an attractive range for tissue engineering, wound healing, and related applications. Electrospun EVOH mats have been shown to support the culturing of smooth muscle cells and fibroblasts. (C) 2002 Elsevier Science Ltd. All rights reserved.