Renal cell carcinoma as a cause of iron deficiency anemia
Renal cell carcinoma as a cause of iron deficiency anemia
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DOI：
10.1016/j.afju.2013.11.001
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发表时间：
2014-03-01
影响因子：
0.5
通讯作者：
Mohammed, Mutwkil M.
中科院分区：
文献类型：
--
作者：
Dowd, Amar A.;Ibrahim, Faisal I.;Mohammed, Mutwkil M.
本文报告一例66岁男性缺铁性贫血16年以上，铁治疗难治。多次大便潜血试验均为阴性。上下内窥镜检查未见出血来源。胶囊肠镜检查未见空肠和回肠血管畸形。病人接受反复输血治疗。腹部超声及腹部CT扫描显示右侧肾脏软组织病变。然后进行ct引导下的活检；组织病理学显示为透明细胞肾细胞癌。行右侧根治性肾切除术；病人的血红蛋白在一个月内急剧上升到14克/分升。贫血对手术的戏剧性反应要求在检查缺铁性贫血的可能原因时考虑肾细胞癌。以前只报告过一例类似病例。(C) 2013泛非泌尿外科医师协会。制作和托管由爱思唯尔B.V.根据CC by - nc - nd许可开放获取。
A case of a 66-years-old male with iron deficiency anemia for more than 16 years, refractory to management with iron therapy is reported. Fecal occult blood test done several times was found to be negative. Upper and lower endoscopy revealed no source of bleeding. Capsule enterscopy showed no vascular malformations in the jejunum and ileum. The patient was managed with repeated blood transfusions. Abdominal ultrasound followed by CT scan abdomen revealed right renal soft tissue lesion. A CT-guided biopsy was then taken; the histopathology revealed a clear cell renal cell carcinoma. Right radical nephrectomy was done; the patient's hemoglobin showed a dramatic increase to 14 g/dL within one month. The dramatic response of the anemia to surgery mandates considering renal cell carcinoma in the workup of the possible causes of iron deficiency anemia. Only one similar case has been previously reported. (C) 2013 Pan African Urological Surgeons' Association. Production and hosting by Elsevier B.V. Open access under CC BY-NC-ND license.