Tracing New Clinical Manifestations in Patients with COVID-19 in Chile and Its Potential Relationship with the SARS-CoV-2 Divergence

Tracing New Clinical Manifestations in Patients with COVID-19 in Chile and Its Potential Relationship with the SARS-CoV-2 Divergence
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DOI:
10.1007/s40475-020-00205-2
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发表时间:
2020-09-01
影响因子:
5.4
通讯作者:
Hernandez-Botero, Sebastian
Hernandez-Botero, Sebastian
中科院分区:
其他
文献类型:
--
作者:
Rodriguez-Morales, Alfonso J.;Rodriguez-Morales, Andrea Gabriela;Hernandez-Botero, Sebastian

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Purpose of Review In this review, we discuss the current implications of the changing genomic epidemiology of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), etiological agent of the Coronavirus Disease 2019 (COVID-19) and its potential relationship with the change of clinical manifestations in patients with confirmed infection.Recent Findings Over the course of the current pandemic, the virus has been found more diverse in new countries. Simultaneously, also new clinical manifestations are observed, particularly more prominent gastrointestinal and neurological findings.Summary SARS-CoV-2/COVID-19 is changing not only its epidemiology, but also its genomic diversity and clinical manifestations, both aspects coupled, needs to be considered in the study of this ongoing pandemic.