Scintimammography with dedicated breast camera detects and localizes occult carcinoma.
Scintimammography with dedicated breast camera detects and localizes occult carcinoma.
复制标题
带有专用乳腺摄像机的闪烁乳房X线照相术可检测并定位隐匿性癌。
作者：
L. R. Coover;G. Caravaglia;P. Kuhn
无标签
这项研究评估了使用标准伽马相机和专用乳房相机作为乳房X光检查和临床检查的辅助手段的核素扫描的实用性。
方法
研究人群包括37名乳房致密、有乳腺癌家族或个人病史的患者。受试者没有任何提示的临床或乳房X光检查结果。在静脉注射(99m)Tc-Sestamibi后，患者使用传统的伽马相机和专用的乳房相机进行成像，在图像采集过程中允许乳房压缩。图片由2名评审员独立解读。所有核素扫描阳性的患者均接受了活检。
结果
专用乳房摄影结果阳性率为13.5%(5/37)。这5例患者活检发现3例癌：1例浸润性小叶癌，1例导管原位癌，1例浸润性管状癌。这3例乳腺癌经临床乳房检查或乳房X光检查均未发现，即使在回顾中也是如此。其中只有一种，管状癌，很容易被标准的伽马相机探测到。
结论
使用专用乳房相机的闪烁钼靶摄影可以加强对乳腺组织致密和乳腺癌高危女性的乳房X光检查和临床乳房检查。
UNLABELLED
This study assessed the utility of scintimammography using a standard gamma-camera and a dedicated breast camera as an adjuvant to mammography and clinical examination.
METHODS
The study population comprised 37 patients with dense breasts and a family or personal history of breast cancer. The subjects had no suggestive clinical or mammographic findings. After intravenous administration of (99m)Tc-sestamibi, the patients were imaged using a conventional gamma-camera and a dedicated breast camera that allowed breast compression during image acquisition. Images were interpreted independently by 2 reviewers. All patients with positive scintimammography findings underwent biopsy.
RESULTS
Dedicated breast camera results were positive in 13.5% (5/37) of patients. Biopsy of these 5 patients yielded 3 carcinomas: an infiltrating lobular carcinoma, a ductal carcinoma in situ, and an infiltrating tubular carcinoma. These 3 carcinomas were undetectable by clinical breast examination or mammography, even on retrospective review. Only one of these, the tubular carcinoma, was readily detectable by the standard gamma-camera.
CONCLUSION
Scintimammography using a dedicated breast camera may augment mammography and clinical breast examination for the subset of women who have dense breast tissue and are at high risk of breast cancer.
影响因子：
19.7
作者：
Rosenberg, RD;Hunt, WC;Linver, MN
通讯作者：
Linver, MN