Cytological profiling: providing more haystacks for chemists' needles.
Cytological profiling: providing more haystacks for chemists' needles.
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DOI：
10.1186/gb-2005-6-8-228
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发表时间：
2005
期刊：
影响因子：
12.3
通讯作者：
King RW
中科院分区：
文献类型：
--
作者：
Lorang J;King RW
A recent study describes how unbiased screening of cellular morphology, followed by affinity purification to identify targets of compounds with interesting effects, can lead to the identification of novel inhibitors. Conventional high-throughput 'chemical genetic' screening seeks to identify small-molecule inhibitors of a specific protein or pathway. A recent study describes how unbiased screening of cellular morphology, followed by affinity purification to identify targets of compounds with interesting effects, can lead to the identification of novel inhibitors.
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DOI：
10.1073/pnas.032516399
发表时间：
2002-02-05
影响因子：
11.1
作者：
Fleming, JA;Lightcap, ES;Blackman, RK
通讯作者：
Blackman, RK
影响因子：
--
作者：
Frank-Kamenetsky M;Zhang XM;Bottega S;Guicherit O;Wichterle H;Dudek H;Bumcrot D;Wang FY;Jones S;Shulok J;Rubin LL;Porter JA
通讯作者：
Porter JA
DOI：
10.2165/00129785-200404060-00004
发表时间：
2004-01-01
期刊：
American journal of pharmacogenomics : genomics-related research in drug development and clinical practice
影响因子：
--
作者：
Berger, Alicia B;Vitorino, Phillip M;Bogyo, Matthew
通讯作者：
Bogyo, Matthew
影响因子：
56.9
作者：
Weinstein, JN;Myers, TG;Paull, KD
通讯作者：
Paull, KD
DOI：
10.1073/pnas.1632587100
发表时间：
2003-08-05
影响因子：
11.1
作者：
Gunther, EC;Stone, DJ;Heyes, MP
通讯作者：
Heyes, MP