GenBank
GenBank
复制标题
DOI：
10.1093/nar/30.1.17
复制
发表时间：
2002-01-01
影响因子：
14.9
通讯作者：
Wheeler, DL
中科院分区：
文献类型：
--
作者：
Benson, DA;Karsch-Mizrachi, I;Wheeler, DL
GenBank序列数据库主要通过直接提交个别实验室和大规模测序项目的序列数据，收录了105000多种不同生物的公开DNA序列。大多数提交是使用BankIt(网络)或Sequin程序提交的，登录号由GenBank工作人员在收到后分配。与EMBL数据库和日本DNA数据库的数据交换有助于确保全面覆盖全球。GenBank数据可以通过NCBI的集成检索系统Entrez获取，该系统集成了主要DNA和蛋白质序列数据库的数据，以及分类学、基因组、图谱、蛋白质结构和领域信息，以及通过PubMed的生物医学文献。序列相似性搜索由BLAST系列程序提供。可通过ftp获得GenBank数据库的完整双月版本和每日更新。NCBI还提供广泛的基于GenBank数据的万维网检索和分析服务。基因库数据库和相关资源可通过国家档案馆主页免费获取，网址为：http://www.ncbi.nlm.nih.gov.
The GenBank sequence database incorporates publicly available DNA sequences of more than 105 000 different organisms, primarily through direct submission of sequence data from individual laboratories and large-scale sequencing projects. Most submissions are made using the BankIt (web) or Sequin programs and accession numbers are assigned by GenBank staff upon receipt. Data exchange with the EMBL Data Library and the DNA Data Bank of Japan helps ensure comprehensive worldwide coverage. GenBank data is accessible through NCBI's integrated retrieval system, Entrez, which integrates data from the major DNA and protein sequence databases along with taxonomy, genome, mapping, protein structure and domain information, and the biomedical literature via PubMed. Sequence similarity searching is provided by the BLAST family of programs. Complete bimonthly releases and daily updates of the GenBank database are available by FTP. NCBI also offers a wide range of World Wide Web retrieval and analysis services based on GenBank data. The GenBank database and related resources are freely accessible via the NCBI home page at http://www.ncbi.nlm.nih.gov.