Feasibility of a Modified Cone-Beam CT Rotation Trajectory to Improve Liver Periphery Visualization during Transarterial Chemoembolization.

Feasibility of a Modified Cone-Beam CT Rotation Trajectory to Improve Liver Periphery Visualization during Transarterial Chemoembolization.
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改进的锥束 CT 旋转轨迹在经动脉化疗栓塞期间改善肝脏外周可视化的可行性。

DOI:
10.1148/radiol.2015142821
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发表时间:
2015
期刊:
影响因子:
19.7
通讯作者:
Lin,MingDe
Lin,MingDe
中科院分区:
医学1区
文献类型:
--
作者:
Schernthaner,RüdigerE;Chapiro,Julius;Sahu,Sonia;Withagen,Paul;Duran,Rafael;Sohn,JaeHo;Radaelli,Alessandro;vanderBom,ImramsjahMartin;Geschwind,Jean-FrançoisH;Lin,MingDe

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目的比较术前超声检查对肝脏的覆盖率和肿瘤的可检测性 磁共振(MR)图像作为参考,以及辐射暴露 锥束计算机断层扫描(CT)的不同旋转 材料和方法15名患者(9名男性和6名女性;平均年龄±标准差, 65岁± 5岁)原发性或继发性肝癌患者 回顾性地纳入本机构审查委员会批准的 study.使用改良的锥形束CT方案,其中C形臂旋转 从+55°到−185°(开弧锥束CT),而不是 −120°至+120°(闭合弧锥束CT)。每个患者 在二月间接受了两次经动脉化疗栓塞 2013年和2014年3月使用闭合弧和开放弧锥束CT(在 第一次和第二次经动脉化疗栓塞疗程, 机构经动脉化疗栓塞方案的一部分)。为 每次锥束CT检查,肝脏体积和肿瘤可检测性 通过使用MR图像作为参考来评估。辐射暴露 通过体模研究进行比较。对于统计分析,采用配对t检验和Wilcoxon符号等级检验 结果平均肝脏体积分别为1695 ± 542和1857 ± 542 cm 3, 闭合弧和开放弧锥束CT的cm 3 ± 571, 分别开放弧锥束CT的覆盖率明显高于 与闭合弧形锥束CT相比(97%对86%的MR成像肝脏 体积,P= .002)。在8名患者(53%)中,肿瘤 部分或完全在闭合弧形锥束CT视野之外, 风景所有肿瘤均在开放弧形锥形束CT视野内。的 采用加权CT指数法进行开放弧锥束CT辐射暴露, 略低于闭弧锥束CT (-5.1%)。结论开放弧锥束CT允许显着改善术中 显示周围型肝肿瘤,同时实现轻微辐射 ©RSNA,2015在线补充材料可用于此 文章.
PurposeTo compare liver coverage and tumor detectability by using preprocedural magnetic resonance (MR) images as a reference, as well as radiation exposure of cone-beam computed tomography (CT) with different rotational trajectories.Materials and MethodsFifteen patients (nine men and six women; mean age ± standard deviation, 65 years ± 5) with primary or secondary liver cancer were retrospectively included in this institutional review board–approved study. A modified cone-beam CT protocol was used in which the C-arm rotates from +55° to −185° (open arc cone-beam CT) instead of −120° to +120° (closed arc cone-beam CT). Each patient underwent two sessions of transarterial chemoembolization between February 2013 and March 2014 with closed arc and open arc cone-beam CT (during the first and second transarterial chemoembolization sessions, respectively, as part of the institutional transarterial chemoembolization protocol). For each cone-beam CT examination, liver volume and tumor detectability were assessed by using MR images as the reference. Radiation exposure was compared by means of a phantom study. For statistical analysis, pairedttests and a Wilcoxon signed rank test were performed.ResultsMean liver volume imaged was 1695 cm3± 542 and 1857 cm3± 571 at closed arc and open arc cone-beam CT, respectively. The coverage of open arc cone-beam CT was significantly higher compared with closed arc cone-beam CT (97% vs 86% of the MR imaging liver volume,P= .002). In eight patients (53%), tumors were partially or completely outside the closed arc cone-beam CT field of view. All tumors were within the open arc cone-beam CT field of view. The open arc cone-beam CT radiation exposure by means of weighted CT index was slightly lower compared with that of closed arc cone-beam CT (−5.1%).ConclusionOpen arc cone-beam CT allowed for a significantly improved intraprocedural depiction of peripheral hepatic tumors while achieving a slight radiation exposure reduction.©RSNA, 2015Online supplemental material is available for this article.