Diagnostic Criteria for Acute Kidney Injury: Present and Future.
Diagnostic Criteria for Acute Kidney Injury: Present and Future.
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DOI：
10.1016/j.ccc.2015.06.001
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发表时间：
2015-10
影响因子：
4.3
通讯作者：
Kellum JA
中科院分区：
文献类型：
--
作者：
Kellum JA
临床诊断中的急性肾损伤，以标准标准为指导，以血清肌酐、尿量或两者的变化为基础。急性肾损伤的严重程度取决于血肌酐升高或尿量减少的程度。同时表现为少尿和氮质血症的患者以及这些损害持续存在的患者更有可能出现更糟糕的疾病和更糟糕的结局。无论是短期还是长期结果，当患者都有某一阶段的AKI时，这两种标准都是更差的。急性心肌梗死的持续时间也是长期预后的重要预测指标，与病情严重程度无关。AKI的新生物标记物可能在很大程度上有助于AKI患者的风险评估和评估。
Acute kidney injury in a clinical diagnosis guided by standard criteria based on changes in serum creatinine, urine output or both. Severity of acute kidney injury is determined by the magnitude of increase in serum creatinine or decrease in urine output. Patients manifesting both oliguria and azotemia and those in which these impairments are persistent are more likely to have worse disease and worse outcomes. Both short- and long-term outcomes are worse when patients have some stage of AKI by both criteria. Duration of AKI was also a significant predictor of long-term outcomes irrespective of severity. New biomarkers for AKI may substantially aid in the risk assessment and evaluation of patients at risk for AKI.