Craving of prescription opioids among veterans with chronic pain.
Craving of prescription opioids among veterans with chronic pain.
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DOI：
10.1097/j.pain.0000000000002598
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发表时间：
2022-10-01
期刊：
影响因子：
7.4
通讯作者：
中科院分区：
文献类型：
--
作者：
摘要 由于慢性疼痛、并发阿片类药物使用障碍和过量死亡的高患病率，美国面临着危机。处方阿片类药物仍然是阿片类药物相关死亡的主要驱动因素。渴望是成瘾的核心症状，但渴望在慢性疼痛患者处方阿片类药物使用中发挥的作用程度尚不清楚。了解慢性疼痛患者的渴望程度对于制定有效的干预措施以支持患者逐渐减少阿片类药物至关重要。目前的工作结合了从 (1) 旧金山 VA 医疗保健系统疼痛专科护理诊所筛选的 2152 名退伍军人收集的数据和 (2) 从 VA 企业数据仓库获得的医疗记录。我们发现患有慢性疼痛的退伍军人对处方阿片类药物的渴望较低，66.4% 的样本报告没有渴望，33.6% 的人报告渴望。我们还发现，渴望与吗啡每日当量剂量和疼痛严重程度有较小的相关性，但与抑郁症的相关性更强。患有慢性疼痛的退伍军人对处方阿片类药物的渴望是复杂的。讨论了与慢性疼痛症状、精神合并症和人口统计相关的研究结果。
Abstract The United States faces a crisis because of the high prevalence of chronic pain, concurrent opioid use disorder, and overdose deaths. Prescription opioids remain a primary driver of opioid-related deaths. Craving is a core symptom of addiction, yet the degree to which craving plays a role in prescription opioid use among patients with chronic pain is unknown. Understanding the degree to which craving should be considered in patients with chronic pain is critical for developing effective interventions for supporting patients through opioid tapering. The current work combines data collected from (1) 2152 veterans screened for eligibility at a pain specialty care clinic at the San Francisco VA Health Care System and (2) medical records obtained from the VA Corporate Data Warehouse. We found that prescription opioid craving among veterans with chronic pain was low, with 66.4% of the sample reporting no craving and 33.6% reporting craving. We also found that craving had a small association with morphine equivalent daily dose and pain severity but was more strongly associated with depression. Craving of prescription opioids among veterans with chronic pain is complex. Findings are discussed in relation to chronic pain symptoms, psychiatric comorbidities, and demographics.
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影响因子：
2.3
作者：
Baxley, Catherine;Weinstock, Jeremiah;Garner, Annie A.
通讯作者：
Garner, Annie A.
CDC规定慢性疼痛的阿片类药物的指南 - 美国，2016年。
DOI：
10.1001/jama.2016.1464
发表时间：
2016-04-19
期刊：
JAMA
影响因子：
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作者：
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