Diagnostic capacity of the keratoconus match index and keratoconus match probability in subclinical keratoconus

Diagnostic capacity of the keratoconus match index and keratoconus match probability in subclinical keratoconus
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DOI:
10.1016/j.jcrs.2013.08.064
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发表时间:
2014-06-01
影响因子:
2.8
通讯作者:
Seitz, Berthold
Seitz, Berthold
中科院分区:
医学2区
文献类型:
--
作者:
Labiris, Georgios;Giarmoukakis, Athanassios;Seitz, Berthold

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目得:目的:评价眼反应分析仪的圆锥角膜匹配指数(KMI)和圆锥角膜匹配概率(KMP)分类对圆锥角膜可疑眼的诊断能力。单位:德国洪堡萨尔兰大学临床眼科。设计:对比病例系列。方法:比较圆锥角膜可疑眼和正常眼的KMI和KMP参数。计算所有可疑眼的定量圆锥角膜百分比指数。根据最薄角膜厚度(TCT)将可疑圆锥角膜患者分为2个亚组:亚组1(TCT 520 μ m)。KMI的总体预测准确性使用受试者工作特征(ROC)曲线进行评估。结果:可疑角膜炎组(50眼)KMI平均值为0.41 ± 0.29(SD),对照组(50眼)为0.94 ± 0.29(P
PURPOSE: To evaluate the diagnostic capacity of the Ocular Response Analyzer's keratoconus match index (KMI) and keratoconus match probability (KMP) classification in keratoconussuspect eyes.SETTING: Department of Ophthalmology, University Clinics Saarland, Homburg, Germany.DESIGN: Comparative case series.METHODS: The KMI and KMP parameters in keratoconus-suspect eyes and normal eyes (control group) were compared. The quantitative keratoconus percentage index was calculated for all suspect eyes. According to the thinnest corneal thickness (TCT), keratoconus-suspect eyes were divided into 2 subgroups: subgroup 1 (TCT 520 mu m). The KMI's overall predictive accuracy was assessed using receiver operating characteristic (ROC) curves. The relationship between KMI and a series of Scheimpflug-derived keratoconus-related indices was evaluated using Spearman analysis.RESULTS: The mean KMI was 0.41 +/- 0.29 (SD) in the keratocon us-suspect group (50 eyes) and 0.94 +/- 0.29 in the control group (50 eyes) (P