A NORMATIVE STUDY OF POSTURAL TREMOR OF THE HAND
A NORMATIVE STUDY OF POSTURAL TREMOR OF THE HAND
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DOI：
10.1001/archneur.1982.00510180036009
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发表时间：
1982-01-01
影响因子：
--
通讯作者：
FINDLEY, LJ
中科院分区：
文献类型：
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作者：
WADE, P;GRESTY, MA;FINDLEY, LJ
在97名15-80岁的正常受试者的手的姿势性震颤的振幅，频率和变异性的规范性研究中，震颤使用加速度计进行转导，并通过功率谱分析进行表征。震颤幅度范围为0.0015-0.035-g峰值（主频）。模态震颤幅度为0.01-g峰值，可见震颤的阈值为0.007-g峰值。模态震颤频率恒定在apprx。70岁以上的受试者中为7 Hz，此后降低至约7 Hz。6赫兹。主频率的平均变异范围为2.5 Hz。震颤模式，其特征在于频谱的形状，变化很大，从一个单一的微调峰多个宽峰。超过三分之二的正常受试者表现出复杂的光谱模式，具有1个以上的显著性峰。被动共振的手组织是一个重要因素，在确定占主导地位的震颤频率在大多数科目。许多受试者表现出强烈的，虽然变量，心弹道成分。结果提供了基线数据的药物对震颤的影响的研究，特别是在原发性震颤的情况下，并提供警告，这样的研究需要客观的记录方法进行充分的评价，并需要求助于测量受药物影响的震颤的几个因素。震颤的缩放可以用于参考重力加速度的强度（1.0 g），这提供了简单的数值关系。
In a normative study of amplitude, frequency and variability of postural tremor of the hand in 97 normal subjects, 15-80 yr old, tremor was transduced using accelerometers and characterized by power spectral analysis. Tremor amplitude ranged from a 0.0015-0.035-g peak at the dominant frequency. The modal tremor amplitude was 0.01-g peak, and the threshold for visible tremor was 0.007-g peak. The modal tremor frequency was constant at .apprx. 7 Hz in those subject up to 70 yr old and thereafter decreased to .apprx. 6 Hz. The mean range of variability of the dominant frequency was 2.5 Hz. The tremor pattern, characterized by the shape of spectra, varied greatly from a single finely tuned peak to multiple broad peaks. More than two thirds of normal subjects showed complex spectral patterns with more than 1 peak of significance. Passive resonance of the hand tissues was an important factor in determining dominant tremor frequencies in most subjects. Many subjects showed a strong, albeit variable, cardioballistic component. Results provide baseline data for studies of the effects of drugs on tremor, particularly in cases of essential tremor, and provide warnings that such studies require objective recording methods for adequate evaluation and need recourse to measurement of several factors of the tremor affected by a drug. A scaling of tremor can be used in terms of reference to the strength of gravitational acceleration (1.0 g), which provides simple numerical relationships.