Genetic linkage and bipolar disorder: a cautionary note.
Genetic linkage and bipolar disorder: a cautionary note.
复制标题
遗传连锁和双相情感障碍：警告。
DOI：
10.1016/s0165-0327(01)00438-4
复制
发表时间：
2001
影响因子：
6.6
通讯作者：
Baron,M
中科院分区：
文献类型：
--
作者：
Baron,M
ConclusionThe foregoing suggests caution in accepting linkage to 18p11 or 21q22 as established or confirmed. Likewise the premature dismissal of possible linkage to Xq28 may not be warranted pending further study. Linkage studies of large data sets, with adequate coverage of the genome, sufficient power to detect gene loci of modest effects, and standardized methods, may shed more light on the possible role of the BP putative loci. Several such studies are underway. Given the genetic complexity of BP,
