Dose Imaging Detectors for Radiotherapy Based on Gas Electron Multipliers.
Dose Imaging Detectors for Radiotherapy Based on Gas Electron Multipliers.
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DOI：
10.1016/j.nima.2010.07.019
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发表时间：
2011-02-01
期刊：
影响因子：
--
通讯作者：
Solberg KA
中科院分区：
文献类型：
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作者：
Klyachko AV;Friesel DL;Kline C;Liechty J;Nichiporov DF;Solberg KA
带电粒子治疗的新技术和现代动态束流输送系统的广泛使用需要新的束流监测设备和精确的2D剂量测量系统来验证输送的剂量分布。我们正在开发基于气体电子倍增器(GEM)的剂量成像探测器，目标是提高剂量测量的线性度、位置和时间分辨率，并最终实现使用扫描束技术进行治疗前剂量分布验证和剂量传输监测。一台10×10 cm~2双宝石探测器样机已在205 MeV质子束上进行了电读出和光学读出实验。电子交叉条带读数的初步结果表明，响应速度快，位置分辨率为单像素(4 Mm)。在光学读出模式下，该探测器的线扩展函数的σ=0.70 mm。在两种读出模式下，探测器的响应都是线性的，最高剂量率为50Gymin，在深度剂量分布测量中充分表示了Bragg峰。
New techniques in charged particle therapy and widespread use of modern dynamic beam delivery systems demand new beam monitoring devices as well as accurate 2D dosimetry systems to verify the delivered dose distribution. We are developing dose imaging detectors based on gas electron multipliers (GEM) with the goal of improving dose measurement linearity, position and timing resolution, and to ultimately allow pre-treatment verification of dose distributions and dose delivery monitoring employing scanning beam technology. A prototype 10×10 cm2 double-GEM detector has been tested in the 205 MeV proton beam using electronic and optical readout modes. Preliminary results with electronic cross-strip readout demonstrate fast response and single-pixel (4 mm) position resolution. In optical readout mode, the line spread function of the detector was found to have σ=0.7 mm. In both readout modes, the detector response was linear up to dose rates of 50 Gy/min, with adequate representation of the Bragg peak in depth-dose profile measurements.