Does marijuana "blunt" smoking contribute to nicotine exposure?: Preliminary product testing of nicotine content in wrappers of cigars commonly used for blunt smoking
Does marijuana "blunt" smoking contribute to nicotine exposure?: Preliminary product testing of nicotine content in wrappers of cigars commonly used for blunt smoking
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DOI：
10.1016/j.drugalcdep.2016.09.007
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发表时间：
2016-11-01
影响因子：
4.2
通讯作者：
Pickworth, Wallace B.
中科院分区：
文献类型：
--
作者：
Peters, Erica N.;Schauer, Gillian L.;Pickworth, Wallace B.
简介：一种日益流行的大麻消费方法是吸食“blunts”雪茄产品，其中部分或全部烟草填充物被去除并用大麻重新包装。即使在制作钝器的过程中从雪茄产品中除去所有烟草填料，尼古丁也可能存在于雪茄产品的包装纸中。这项初步分析量化了通常用于直接吸食的雪茄产品茄衣中的尼古丁含量。方法：测试了五种雪茄产品（3支大雪茄，2支小雪茄），得出雪茄长度、直径、重量和茄衣重量的物理特征。通过气相色谱/质谱分析每个雪茄产品包装纸中的尼古丁浓度。每个雪茄产品茄衣中的总尼古丁含量计算为雪茄茄衣重量与茄衣中尼古丁浓度的乘积。 结果：根据产品的不同，雪茄茄衣占整个雪茄制品重量的 8% 到 18%。雪茄茄衣中的总尼古丁含量为每支雪茄 1.2 至 6.0 毫克。 讨论：所有 5 种测试的雪茄产品的茄衣都含有可量化水平的尼古丁，这表明 blunts 的使用者可能会接触到一定程度的尼古丁（烟草的成瘾成分）。未来需要进行实验研究来检查典型的钝性吸烟的尼古丁输送效率，以及量化个体每天吸烟次数的监测研究，以评估钝性吸烟对尼古丁依赖的影响。 (C) 2016 Elsevier Ireland Ltd. 保留所有权利。
Introduction: An increasingly popular method of consuming marijuana is through the smoking of "blunts," cigar products in which some or all of the tobacco filler is removed and repacked with marijuana. Even if all tobacco filler is removed from the cigar product in the process of making blunts, nicotine may be present in the wrapper of the cigar product. This preliminary analysis quantified the nicotine content in wrappers of cigar products commonly used for blunt smoking.Methods: Five cigar products (3 large cigars, 2 cigarillos) were tested, yielding physical characteristics of cigar length, diameter, weight, and wrapper weight. Nicotine concentration in the wrapper of each cigar product was analyzed via gas chromatography/mass spectrometry. Total nicotine content in the wrapper of each cigar product was computed as the product of cigar wrapper weight and nicotine concentration in wrapper.Results: Depending on the product, the cigar wrapper contributed between 8 and 18% of the weight of the entire cigar article. Total nicotine content in the cigar wrapper ranged from 1.2 to 6.0 mg per cigar.Discussion: All 5 tested cigar products had wrappers that contain quantifiable levels of nicotine, indicating that users of blunts may expose themselves to some degree of nicotine, the addictive component of tobacco. Future experimental studies that examine the efficiency of nicotine delivery from typical blunt smoking, as well as surveillance studies that quantify the number of blunts smoked by an individual per day, are needed to evaluate the contribution of blunt smoking to nicotine dependence. (C) 2016 Elsevier Ireland Ltd. All rights reserved.