[Therapy for clearing heat and resolving phlegm in treatment of systemic inflammatory response syndrome in acute deterioration stage of chronic obstructive pulmonary disease: a randomized controlled trial].
[Therapy for clearing heat and resolving phlegm in treatment of systemic inflammatory response syndrome in acute deterioration stage of chronic obstructive pulmonary disease: a randomized controlled trial].
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DOI：
10.3736/jcim20090202
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发表时间：
2009-02-01
期刊：
影响因子：
--
通讯作者：
Hao, Xiao-Mei
中科院分区：
文献类型：
--
作者：
Chen, Ning;Li, Hui;Hao, Xiao-Mei
目的：探讨清热化痰法对慢性阻塞性肺疾病（COPD）急性加重期全身炎症反应综合征（SIRS）及血清降钙素原（PCT）水平的影响。将100例COPD急性加重期SIRS患者随机分为治疗组和对照组对照组50例。治疗组在西医常规治疗的基础上加用清热化痰中药治疗，对照组仅用西医常规治疗。两组患者均治疗1周。观察两组患者治疗后第1、3、7天血清PCT水平的变化，并记录第1、7天临床症状评分，以判断疗效。
OBJECTIVE: To investigate the effects of traditional Chinese medicine (TCM) therapy for clearing heat and resolving phlegm on systemic inflammatory response syndrome (SIRS) in acute deterioration stage of chronic obstructive pulmonary disease (COPD) and the serum procalcitonin (PCT) level.METHODS: One hundred patients suffering from SIRS in acute deterioration stage of COPD were included and randomly divided into treatment group (50 cases) and control group (50 cases). Patients in the treatment group were treated with routine Western medicine and Chinese herbal medicine for clearing away heat and eliminating phlegm, while patients in the control group were treated with routine Western medicine only. Patients in the two groups were treated for one week. The serum PCT levels in the two groups were measured at days 1, 3, and 7, and clinical symptom scores were recorded at days 1 and 7 in hospital to determine the effects.RESULTS: Clinical symptom scores in the two groups decreased after the treatment (P