CORTICAL CONNECTIONS OF MT IN 4 SPECIES OF PRIMATES - AREAL, MODULAR, AND RETINOTOPIC PATTERNS
CORTICAL CONNECTIONS OF MT IN 4 SPECIES OF PRIMATES - AREAL, MODULAR, AND RETINOTOPIC PATTERNS
复制标题
DOI：
10.1017/s0952523800000213
复制
发表时间：
1990-08-01
影响因子：
1.9
通讯作者：
KAAS, JH
中科院分区：
文献类型：
--
作者：
KRUBITZER, LA;KAAS, JH
皮质连接进行了调查，限制注射WGA-HRP的中颞视觉区，MT，在松鼠猴，猫头鹰猴，绒猴，和galagos的不同部分。将皮质压平并切向切片，以便于分析连接的区域模式。在实验的情况下，脑切片细胞色素氧化酶（CO）反应或染色的髓鞘被用来划定枕叶和颞叶皮层的视觉区和额叶的视觉区。主要调查结果如下：（1）结构分析表明，除了公认的视觉区17区（V-I）、18区（V-II）和MT外，三种新大陆猴和原猿类星系都有视觉区DL、DI、DM、MST和FST。(2)对这些区域大小的测量表明，这些灵长类动物大约三分之一的新皮层被这八个视觉区域所占据，但它们在昼行性的绒猴和松鼠猴的新皮层中所占的比例要比夜行性的猫头鹰猴和加拉戈斯猴大一些。白天活动的灵长类动物也有更多的新皮层用于区域17，18和DL，而MT较少。这些差异与白天活动的灵长类动物对物体细节和颜色视觉的特化是一致的。(3)在所有四种灵长类动物中，MT中的受限位置接收来自区域17中的短蜿蜒行神经元和区域18中的几个神经元带的主要输入。(4)MT的主要前馈投影是到与MT的嘴侧半部分相邻的两个视觉区，MST区，MST区和FST区。其他同侧连接与DL，DI，在某些情况下DM，部分下颞（IT）皮质和后顶叶皮质。(5)在松鼠猴中，尾侧和吻侧MT的不同部位，代表中央视觉的MT尾侧部分与DL和IT的连接密度高于其他部位。DL和IT皮层都强调中央视觉。(6)在额叶，MT与额腹侧区（FV）有密集的联系，但与额眼区（FEF）没有联系。(7)与另一半球MT匹配的位置，MT的胼胝体连接最密集，而不是MT的外边界代表垂直子午线。稀疏计算连接的目标包括FST、MST和DL。结果支持以下结论：（1）原猴和新大陆猴至少有10个共同的视觉和视区，（2）MT的连接在四种灵长类动物中是非常一致的，（3）视觉子系统在17和18区的解剖分离是所有灵长类动物所共有的，（4）代表中央视觉的MT部分与强调中央视觉的视区之间的联系更紧密;（5）MT及其相关的MST和FST在夜间活动的灵长类动物中所占的比例比白天活动的灵长类动物高。
Cortical connections were investigated by restricting injections of WGA-HRP to different parts of the middle temporal visual area, MT, in squirrel monkeys, owl monkeys, marmosets, and galagos. Cortex was flattened and sectioned tangentially to facilitate an analysis of the areal patterns of connections. In the experimental cases, brain sections reacted for cytochrome oxidase (CO) or stained for myelin were used to delimit visual areas of occipital and temporal cortex and visuomotor areas of the frontal lobe. Major findings are as follows: (1) The architectonic analysis suggests that in addition to the commonly recognized visual fields, area 17 (V-I), area 18 (V-II), and MT, all three New World monkeys and prosimian galagos have visual areas DL, DI, DM, MST, FST. (2) Measurements of the size of these areas indicate that about a third of the neocortex in these primates is occupied by the eight visual areas, but they occupy a somewhat larger proportion of neocortex in the diurnal marmosets and squirrel monkeys than the nocturnal owl monkeys and galagos. The diurnal primates also have proportionally more neocortex devoted to areas 17, 18, and DL and less to MT. These differences are compatible with view that diurnal primates are most specialized for detailed objected and color vision. (3) In all four primates, restricted locations in MT receives major inputs from short meandering rows of neurons in area 17 and several bands of neurons in area 18. (4) Major feedforward projections of MT are to two visual areas adjoining the rostral half of MT, areas MST, areas MST and FST. Other ipsilateral connections are with DL, DI, and in some cases DM, parts of inferotemporal (IT) cortex, and posterior parietal cortex. (5) In squirrel monkeys, whereinjection sites varied from caudal to rostral MT, caudal parts of MT representing central vision connect vision connect more density to DL and IT than other parts. Both DL and IT cortex emphasize central vision. (6) In the frontal lobe, MT has dense connections with the frontal ventral area (FV), but not with the frontal eye field (FEF). (7) Callosal connections of MT are most dense with matched locations in MT of the other hemisphere, rather that with the outer boundary of MT representing the vertical meridian. Targets of sparser calosal connections include FST, MST, and DL. The results supports the conclusions that (1) prosimian and New World monkeys have at least ten visual and visuomotor areas in common, (2) the connections of MT are remarkably consistent across four species of primates, (3) the anatomical segregation of visual subsystems in areas 17 and 18 is common to all primates, (4) connections from the part of MT representing central vision with visual areas emphasizing central vision are more dense, and (5) MT and the associated fields MST and FST occupy proportionally more cortex in nocturnal than diurnal primates.