Iron-Deficiency Anemia in Infancy and Social Emotional Development in Preschool-Aged Chinese Children
Iron-Deficiency Anemia in Infancy and Social Emotional Development in Preschool-Aged Chinese Children
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DOI：
10.1542/peds.2010-1659
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发表时间：
2011-04-01
期刊：
影响因子：
8
通讯作者：
Chen, Chunming
中科院分区：
文献类型：
--
作者：
Chang, Suying;Wang, Li;Chen, Chunming
目的：我们的目的是比较3组非贫血的4岁儿童的情感和行为：婴儿期缺铁性贫血（IDA）儿童，其贫血在24个月前未得到纠正（慢性IDA）（n = 27）; 24个月前贫血得到纠正的婴儿期IDA儿童（校正IDA）（n = 70）;和儿童谁是非贫血的婴儿期和24个月（n = 64）。方法：母亲和儿童二对被邀请到当地的诊所。儿童的社会参考，谨慎，挫折容忍行为，并在实验室中遇到的一组情况下，包括自由发挥，陌生人的做法，新奇的玩具，延迟满足观察。整个过程都被录了下来。儿童的情感和行为显示编码使用时间采样（5秒段）的代码计划。铁的儿童状况的基础上测定的血红蛋白浓度与氰高铁血红蛋白法在婴儿期和24个月和4岁的年龄获得的手指针刺血样中测定结果：儿童谁有慢性IDA在婴儿期表现出较少的积极影响，挫折容忍度，更多的被动行为，更多的身体自我安慰的陌生人的做法和延迟的满足。相比之下，行为和影响的儿童的贫血得到纠正之前的24个月的年龄是可比的那些儿童谁是nonanemic整个infanty.CONCLUSION：结果点的潜在好处，防止铁缺乏症在婴儿期和治疗之前，它成为慢性或严重的。儿科2011; 127：e927-e933
OBJECTIVE: We aimed to compare affect and behavior of 3 groups of nonanemic 4-year-old children: children with iron-deficiency anemia (IDA) in infancy whose anemia was not corrected before 24 months (chronic IDA) (n = 27); children with IDA in infancy whose anemia was corrected before 24 months (corrected IDA) (n = 70); and children who were nonanemic in infancy and at 24 months (n = 64).METHOD: Mother and child dyads were invited to a local clinic room. Children's social referencing, wariness, frustration-tolerance behavior, and affect were observed during a set of situations encountered in the laboratory, including free play, stranger approach, novel toy, and delay of gratification. The whole procedure was videotaped. The children's affective and behavioral displays were coded by using a time-sampling (5-second segments) code scheme. Iron status of children was determined on the basis of hemoglobin concentration measured with the cyanomethemoglobin method in blood samples obtained by fingerstick in infancy and at the ages of 24 months and 4 years.RESULTS: Children who had chronic IDA in infancy displayed less positive affect, less frustration tolerance, more passive behavior, and more physical self-soothing in the stranger approach and delay of gratification. In contrast, the behavior and affect of children whose anemia was corrected before the age of 24 months were comparable to those of children who were nonanemic throughout infancy.CONCLUSION: The results point to the potential benefits of preventing iron deficiency in infancy and treating it before it becomes chronic or severe. Pediatrics 2011; 127: e927-e933