Synthesis, Molecular Docking, and Biological Evaluation of Novel Triazole Derivatives as Antifungal Agents

Synthesis, Molecular Docking, and Biological Evaluation of Novel Triazole Derivatives as Antifungal Agents
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新型抗真菌三唑衍生物的合成、分子对接和生物学评价

DOI:
10.1111/j.1747-0285.2010.01038.x
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发表时间:
2010-12
影响因子:
3
通讯作者:
Honggang Hu
Honggang Hu
中科院分区:
医学4区
文献类型:
--
作者:
Qiuye Wu;Xiaoyun Chai;Qingguo Meng;Zhongjun Guan;Shichong Yu;Yuanying Jiang;Honggang Hu

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Twenty‐eight novel triazole derivatives (compounds 1a‐v, 2a‐f) have been synthesized for structure–activity relationship studies as antifungal agents. The compounds were designed on the basis of the structure of fluconazole and molecular modeling of the a
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