Modality-specific attention and multisensory integration of emotions in schizophrenia: Reduced regulatory effects
Modality-specific attention and multisensory integration of emotions in schizophrenia: Reduced regulatory effects
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DOI：
10.1016/j.schres.2010.04.010
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发表时间：
2010-09-01
影响因子：
4.5
通讯作者：
de Gelder, B.
中科院分区：
文献类型：
--
作者：
de Jong, J. J.;Hodiamont, P. P. G.;de Gelder, B.
背景：情绪知觉缺陷在精神分裂症患者中是一个公认的现象，研究通常使用单模态情绪任务，呈现情绪面孔或情绪发声。我们在之前的两项研究中引入了双峰情绪条件，以研究视觉和听觉情绪线索的多感觉整合过程。我们现在在我们早期工作的基础上，解决了选择性注意机制对来自多感觉通道的情感线索整合能力的调节作用。方法：我们在原始双峰范式的基础上增加了中性次要分心物条件，以研究模式特异性选择性注意机制。我们将精神分裂症患者（n=50）与非精神分裂症精神病患者（n=46）以及健康对照（n=50）进行比较。一位训练有素的精神科医生使用神经精神病学临床评估表（SCAN 2.1）对患者进行诊断。结果：正如预期的那样，在健康对照中，以及在较小程度上在非精神分裂症精神病患者中，模式特异性注意减弱了情绪面孔和发声的多感觉整合。相反，在精神分裂症患者中，听觉和视觉干扰条件会产生不受影响甚至夸张的多感觉整合。结论：这些结果表明，与健康对照组和非精神分裂症精神病患者相比，精神分裂症患者在试图整合来自多渠道来源的情绪信息时存在模式特异性注意缺陷。对我们的发现的各种解释，以及他们可能的后果，进行了讨论。(C) 2010 Elsevier B.V.版权所有
Background: Deficits in emotion perception are a well-established phenomenon in schizophrenic patients and studies have typically used unimodal emotion tasks, presenting either emotional faces or emotional vocalizations. We introduced bimodal emotion conditions in two previous studies in order to study the process of multisensory integration of visible and audible emotion cues. We now build on our earlier work and address the regulatory effects of selective attention mechanisms on the ability to integrate emotion cues stemming from multisensory channels.Methods: We added a neutral secondary distractor condition to the original bimodal paradigm in order to investigate modality-specific selective attention mechanisms. We compared schizophrenic patients (n=50) to non-schizophrenic psychotic patients (n=46), as well as to healthy controls (n=50). A trained psychiatrist used the Schedules of Clinical Assessment in Neuropsychiatry (SCAN 2.1) to diagnose the patients.Results: As expected, in healthy controls, and to a lesser extent in non-schizophrenic psychotic patients, modality-specific attention attenuated multisensory integration of emotional faces and vocalizations. Conversely, in schizophrenic patients, auditory and visual distractor conditions yielded unaffected and even exaggerated multisensory integration.Conclusions: These results suggest that schizophrenics, as compared to healthy controls and non-schizophrenic psychotic patients, have modality-specific attention deficits when attempting to integrate information regarding emotions that stem from multichannel sources. Various explanations for our findings, as well as their possible consequences, are discussed. (C) 2010 Elsevier B.V. All rights reserved.