Results from a seven-year programme of breast self-examination in 89,010 women.
Results from a seven-year programme of breast self-examination in 89,010 women.
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DOI：
10.1038/bjc.1989.294
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发表时间：
1989-09
影响因子：
8.8
通讯作者：
Elston CW
中科院分区：
文献类型：
--
作者：
Locker AP;Caseldine J;Mitchell AK;Blamey RW;Roebuck EJ;Elston CW
这份报告介绍了一项自1979年以来在诺丁汉市内对大量确定人群进行乳房自我检查(BSE)效果的研究结果。我们检查了一组被邀请参加疯牛病教育的患者的乳房自我检查的效果，并与一组历史对照组进行了比较。研究组没有显示出总体的生存优势，但在后一组中，接受过疯牛病培训的患者13年的精算生存率明显好于没有接受指导的患者(P<0.001)。研究组患者的肿瘤明显较小，更有可能具有较好的组织学分级和淋巴结分期。一项病例对照研究证明了参加疯牛病治疗的价值，尤其是在绝经后妇女中。尽管BSE不像乳房X光检查那样敏感，但使用BSE的患者呈现出更有利的肿瘤特征，而且它在绝经后妇女中的价值支持将其用作乳房X光检查的辅助手段。
This report presents the results of a study into the effect of breast self-examination (BSE) in a large defined population within the City of Nottingham since 1979. We have examined the effect of breast self-examination in a group of patients invited to attend for education in BSE compared with a group of historical controls. No overall survival advantage has been demonstrated for the study group but within the latter group patients who had attended for instruction in BSE had a significantly better actuarial survival at 13 years than those who did not (P less than 0.001). Patients in the study group presented with significantly smaller tumours which were more likely to be of better histological grade and lymph node stage. A case-control study has demonstrated the value of attendance for BSE particularly in post-menopausal women. Although BSE is not as sensitive as mammographic screening, patients who practise it present with more favourable tumour characteristics and its value in post-menopausal women supports its use as an adjunct to mammographic screening.