The gene CBO0515 from Clostridium botulinum strain Hall A encodes the rare enzyme N5-(carboxyethyl) ornithine synthase, EC 1.5.1.24.
The gene CBO0515 from Clostridium botulinum strain Hall A encodes the rare enzyme N5-(carboxyethyl) ornithine synthase, EC 1.5.1.24.
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来自肉毒杆菌 Hall A 菌株的基因 CBO0515 编码稀有酶 N5-（羧乙基）鸟氨酸合酶，EC 1.5.1.24。
DOI：
10.1128/jb.01044-09
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发表时间：
2010
影响因子：
3.2
通讯作者：
Pikis,Andreas
中科院分区：
文献类型：
--
作者：
Thompson,John;Hill,KarenK;Smith,TheresaJ;Pikis,Andreas
对肉毒梭菌Hall A菌株的基因组测序发现了一个基因(CBO0515)，其推测的氨基酸序列与罕见的酶N5-(1-羧乙基)鸟氨酸合成酶有关。为了验证这一假设，我们克隆了CBO0515，并对编码的多肽进行了纯化和鉴定。这种不寻常的基因似乎仅限于属于OFC组1的蛋白水解菌。肉毒杆菌。
Sequencing of the genome ofClostridium botulinumstrain Hall A revealed a gene (CBO0515), whose putative amino acid sequence was suggestive of the rare enzymeN5-(1-carboxyethyl) ornithine synthase. To test this hypothesis, CBO0515 has been cloned, and the encoded polypeptide was purified and characterized. This unusual gene appears to be confined to proteolytic strains assigned to group 1 ofC. botulinum.