Chemoselective RuII-Catalyzed Synthesis of Aryl Thiocyanates and Step-wise Double [2+2+2] Cycloadditions to 2-Aryl Thiopyridines
Chemoselective RuII-Catalyzed Synthesis of Aryl Thiocyanates and Step-wise Double [2+2+2] Cycloadditions to 2-Aryl Thiopyridines
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DOI：
10.1002/ejoc.202000691
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发表时间：
2020-06-22
影响因子：
2.8
通讯作者：
Goswami, Avijit
中科院分区：
文献类型：
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作者：
Bhatt, Divya;Kalaramna, Pratibha;Goswami, Avijit
研究了钌催化的1，6-二炔与炔基硫氰酸酯的分子间[2+2+2]双环加成反应，合成了2-芳基硫代吡啶。芳基硫氰酸酯的化学选择性分离作为初始分子间[2+2+2]环加成产物的结果。该方法操作简单，本质上原子经济。
Ru-II-catalyzed intermolecular double [2+2+2] cycloadditions of 1,6-diynes and alkynylthiocyanates have been developed for the synthesis of 2-aryl thiopyridines. Aryl thiocyanates were isolated chemoselectively as a result of initial intermolecular [2+2+2] cycloaddition product. The method offers operational simplicity and is atom economical in nature.