Deficient recognition of emotional prosody in primary focal dystonia
Deficient recognition of emotional prosody in primary focal dystonia
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DOI：
10.1111/j.1468-1331.2010.03144.x
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发表时间：
2011-02-01
影响因子：
5.1
通讯作者：
Schroeder, C.
中科院分区：
文献类型：
--
作者：
Nikolova, Z. T.;Fellbrich, A.;Schroeder, C.
背景：原发性肌张力障碍是一种主要由基底节功能障碍引起的运动障碍。除了运动控制，纹状体-苍白球结构还执行非运动功能，包括认知和情绪信息的处理。先前的研究已经证明，原发性局灶性肌张力障碍患者对情绪面孔的识别能力不足。然而，肌张力障碍患者的情绪韵律加工是否也受到影响尚不清楚。方法：本研究中，30例原发性颈肌张力障碍患者和30名健康对照受试者被要求根据他们的情绪韵律(愤怒、高兴、放松、悲伤)对听觉呈现词进行分类。结果：对命中率和反应时的分析显示，颈性肌张力障碍患者对愤怒语调词的判断能力显著降低。附加心理评定量表(SCL-90R)显示躯体化、焦虑和抑郁症状的CD患者的心理困扰程度更高。结论：这些发现进一步深入了解了基底节参与情绪韵律的加工，强调了识别CD患者的精神病理症状作为运动障碍的补充的重要性。
Background:Primary dystonia is a movement disorder attributed mainly to basal ganglia dysfunction. Besides motor control, striatopallidal structures are known to implement also non-motor functions including processing of cognitive and emotional information. Previous research has already demonstrated deficient recognition of emotional faces in patients with primary focal dystonia. However, it remains elusive if emotional prosody processing in dystonia is also affected.Methods:In this study, 30 patients with primary cervical dystonia (CD) and 30 healthy control subjects (HC) had to classify auditory presented words according to their emotional prosody (angry, happy, relaxed, sad).Results:Analysis of hit rates and reaction times revealed a significantly poorer performance of patients with CD in judging angrily intonated words. Additional psychological assessment (SCL-90 R) demonstrated a higher level of psychological distress in patients with CD who displayed symptoms of somatization, anxiety and depression.Conclusions:Together these findings bring further insight into the basal ganglia involvement in processing of emotional prosody and emphasize the importance to identify the psychopathological symptoms in patients with CD as complementary to the motor deficit.