Acute myopericarditis after diphtheria, tetanus, and polio vaccination
Acute myopericarditis after diphtheria, tetanus, and polio vaccination
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DOI：
10.1378/chest.120.2.671
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发表时间：
2001-08-01
期刊：
影响因子：
9.6
通讯作者：
Cohen, A
中科院分区：
文献类型：
--
作者：
Boccara, F;Benhaiem-Sigaux, N;Cohen, A
我们报告第一例心肌心包炎后，三联疫苗接种白喉，破伤风，脊髓灰质炎病毒的年轻成年人。他在接种疫苗后2天出现发热、急性胸痛和弥漫性ST段抬高。二维超声心动图检查结果正常。肌内膜活检显示间质水肿伴红细胞渗出。实验室检查结果显示炎症综合征和循环免疫复合物升高。他在接受大剂量阿司匹林治疗后几天内康复，3个月随访时无并发症。我们讨论了感染性或超敏性心肌炎的不同假说。
We report the first case of myopericarditis after triple vaccination against diphtheria, tetanus, and poliovirus in a young adult. He presented with fever, acute chest pain, and diffuse ST-segment elevation 2 days after vaccination. Two-dimensional echocardiography findings were normal. Endomyocardial biopsy showed interstitial edema with diapedesis of erythrocytes. Laboratory findings showed inflammatory syndrome and elevated circulating immune complexes. He recovered within a few days with high-dose aspirin treatment and was without complications at 3-month follow-up. We discuss the different hypotheses for infective or hypersensitivity myocarditis.