Incidence of human immunodeficiency virus among male-to-female transgendered persons in San Francisco
Incidence of human immunodeficiency virus among male-to-female transgendered persons in San Francisco
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DOI：
10.1097/00126334-200112010-00012
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发表时间：
2001-12-01
期刊：
影响因子：
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通讯作者：
McFarland, W
中科院分区：
文献类型：
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作者：
Kellogg, TA;Clements-Nolle, K;McFarland, W
目的：估计 1997 年 7 月至 2000 年 6 月期间在旧金山公共咨询和检测点反复检测 HIV 抗体的男女变性者（MtF 变性者）的 HIV 感染率。方法：使用当前检测的日期和结果以及上次检测的自我报告日期和结果来确定 HIV 血清转化并估计观察人次。使用多变量比例风险分析确定与 HIV 血清转化独立相关的因素。结果：根据 155 名重复测试者和 167.7 人年观察中的 13 次血清转化，HIV 发病率为每 100 人年 7.8 例（95% 置信区间 [CI]，4.6-12.3）。非裔美国人种/族裔（调整后相对风险比 [HR]，5.0；95% CI，1.5-16.2）和无保护的接受性肛交 MR，3.9 ~ 95% CI，1.2-13.1）是 HIV 血清转化的独立预测因素。结论：HIV 目前在旧金山的 MtF 变性者中以极高的速度传播，尤其是那些非洲人美国人。
Objective: To estimate HIV incidence among male-to-female transgendered persons (MtF transgendered persons) who repeatedly tested for HIV antibodies at Public San Francisco counseling and testing sites between July 1997 and June 2000.Methods: HIV seroconversions were identified and person-time of observation were estimated using the date and result of the current test and the self-reported date and result of the previous test. Factors independently associated with HIV seroconversion were determined using multivariable proportional hazard analysis.Results: HIV incidence was 7.8 per 100 person-years (95% confidence intervals [CI], 4.6-12.3) based on 13 seroconversions among 155 repeat testers with 167.7 person-years of observation. African-American race/ethnicity (adjusted relative hazard ratio [HR], 5.0; 95% CI, 1.5-16.2) and unprotected receptive anal intercourse MR, 3.9 95% CI, 1.2-13.1) were independent predictors of HIV seroconversion.Conclusions: HIV is currently spreading at an extremely high rate among MtF transgendered persons in San Francisco, especially those Who are African Americans.