Ultrastructure of the gastric mucosa harboring Campylobacter-like organisms.
Ultrastructure of the gastric mucosa harboring Campylobacter-like organisms.
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DOI：
10.1093/ajcp/86.5.575
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发表时间：
1986-11
影响因子：
3.5
通讯作者：
Xiao Geng Chen;P. Correa;J. Offerhaus;Elsie Rodriguez;F. Janney;E. Hoffmann;James G. Fox;F. Hunter;S. Diavolitsis
中科院分区：
文献类型：
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作者：
Xiao Geng Chen;P. Correa;J. Offerhaus;Elsie Rodriguez;F. Janney;E. Hoffmann;James G. Fox;F. Hunter;S. Diavolitsis
弯曲杆菌样生物（CLOs）与胃粘膜病变之间的关系研究了59个连续的活检。采用苏木精、伊红、Warthin-Starry银染色，高分辨率光镜（HRLM）和透射电镜（TEM）。这些生物与中央凹细胞密切接触，显示出丰富的吞噬溶酶体和细胞间复合物的改变。静息期的壁细胞附近也可见CLOs，其中一些细胞表现为退行性改变。这些发现是根据最近的报道将CLOs与胃炎的原因联系起来进行讨论的。
The association between Campylobacter-like organisms (CLOs) and lesions of the gastric mucosa was studied in 59 consecutive biopsies. Hematoxylin and eosin and Warthin-Starry silver stains, as well as high-resolution light microscopy (HRLM) and transmission electron microscopy (TEM), were used. The organisms were found in intimate contact with foveolar cells showing abundant phagolysosomes and alterations of the intercellular complexes. CLOs also were seen in close proximity of parietal cells in resting phase, some of which showed degenerative changes. The findings are discussed in light of recent reports linking CLOs to the cause of gastritis.